[HTML][HTML] The dual role of iNOS in cancer

F Vannini, K Kashfi, N Nath - Redox biology, 2015 - Elsevier
Nitric oxide (NO) is one of the 10 smallest molecules found in nature. It is a simple gaseous
free radical whose predominant functions is that of a messenger through cGMP. In …

Mechanistic links between obesity, diabetes, and blood pressure: role of perivascular adipose tissue

SN Saxton, BJ Clark, SB Withers… - Physiological …, 2019 - journals.physiology.org
Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …

[HTML][HTML] The endothelium and its role in regulating vascular tone

A Sandoo, JJCSV van Zanten, GS Metsios… - The open …, 2010 - ncbi.nlm.nih.gov
The endothelium forms an important part of the vasculature and is involved in promoting an
atheroprotective environment via the complementary actions of endothelial cell-derived …

Nitric oxide and the immune response

C Bogdan - Nature immunology, 2001 - nature.com
During the past two decades, nitric oxide (NO) has been recognized as one of the most
versatile players in the immune system. It is involved in the pathogenesis and control of …

Arginine metabolism: nitric oxide and beyond

G Wu, SM Morris Jr - Biochemical Journal, 1998 - portlandpress.com
Arginine is one of the most versatile amino acids in animal cells, serving as a precursor for
the synthesis not only of proteins but also of nitric oxide, urea, polyamines, proline …

Endothelial dysfunction in obesity

A Engin - Obesity and lipotoxicity, 2017 - Springer
Chronic inflammatory state in obesity causes dysregulation of the endocrine and paracrine
actions of adipocyte-derived factors, which disrupt vascular homeostasis and contribute to …

Antiviral actions of interferons

CE Samuel - Clinical microbiology reviews, 2001 - Am Soc Microbiol
Tremendous progress has been made in understanding the molecular basis of the antiviral
actions of interferons (IFNs), as well as strategies evolved by viruses to antagonize the …

[PDF][PDF] Nitric oxide and superoxide in inflammation

T Guzik, R Korbut, T Adamek-Guzik - J physiol pharmacol, 2003 - jpp.krakow.pl
Nitric oxide (NO) and reactive oxygen species exert multiple modulating effects on
inflammation and play a key role in the regulation of immune responses. They affect virtually …

The yin and yang of nitric oxide in cancer progression

AJ Burke, FJ Sullivan, FJ Giles, SA Glynn - Carcinogenesis, 2013 - academic.oup.com
Nitric oxide (NO) is a short-lived, pleiotropic molecule that affects numerous critical functions
in the body. Presently, there are markedly conflicting findings in the literature regarding NO …

Reactive oxygen and reactive nitrogen intermediates in innate and specific immunity

C Bogdan, M Röllinghoff, A Diefenbach - Current opinion in immunology, 2000 - Elsevier
Nitric oxide, nitric oxide derivatives and reactive oxygen intermediates are toxic molecules of
the immune system which contribute to the control of microbial pathogens and tumors. There …