A meta-analysis of cognitive deficits in first-episode major depressive disorder
BACKGROUND: Recurrent-episode Major Depressive Disorder (MDD) is associated with a
number of neuropsychological deficits. To date, less is known about whether these are …
number of neuropsychological deficits. To date, less is known about whether these are …
Major depressive disorder
Major depressive disorder (MDD) is a debilitating disease that is characterized by
depressed mood, diminished interests, impaired cognitive function and vegetative …
depressed mood, diminished interests, impaired cognitive function and vegetative …
Saffron in the treatment of depression, anxiety and other mental disorders: Current evidence and potential mechanisms of action
Background Depression and anxiety are two common mental health problems with high
economic and social costs. Currently, a number of treatments are available for patients with …
economic and social costs. Currently, a number of treatments are available for patients with …
Nutrition and depression: implications for improving mental health among childbearing-aged women
LM Bodnar, KL Wisner - Biological psychiatry, 2005 - Elsevier
Adequate nutrition is needed for countless aspects of brain functioning. Poor diet quality,
ubiquitous in the United States, may be a modifiable risk factor for depression. The objective …
ubiquitous in the United States, may be a modifiable risk factor for depression. The objective …
Pharmacological effects of Lu AA21004: a novel multimodal compound for the treatment of major depressive disorder
A Mørk, A Pehrson, LT Brennum, SM Nielsen… - … of Pharmacology and …, 2012 - ASPET
1-[2-(2, 4-Dimethylphenyl-sulfanyl)-phenyl]-piperazine (Lu AA21004) is a human (h)
serotonin (5-HT) 3A receptor antagonist (Ki= 3.7 nM), h5-HT7 receptor antagonist (K i= 19 …
serotonin (5-HT) 3A receptor antagonist (Ki= 3.7 nM), h5-HT7 receptor antagonist (K i= 19 …
Leptin: a potential novel antidepressant
Leptin, a hormone secreted from adipose tissue, was originally discovered to regulate body
weight. The localization of the leptin receptor in limbic structures suggests a potential role for …
weight. The localization of the leptin receptor in limbic structures suggests a potential role for …
Sexual dysfunction in depression and anxiety: conceptualizing sexual dysfunction as part of an internalizing dimension
SM Laurent, AD Simons - Clinical psychology review, 2009 - Elsevier
Sexual dysfunction is often implicated in depression and anxiety disorders, but the current
nosology of sexual dysfunction, depression, and anxiety (ie, DSM-IV) does not adequately …
nosology of sexual dysfunction, depression, and anxiety (ie, DSM-IV) does not adequately …
[HTML][HTML] Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment
FJ McMahon, S Buervenich, D Charney… - The American Journal of …, 2006 - cell.com
Depressive disorders account for a large and increasing global burden of disease. Although
the condition of many patients improves with medication, only a minority experience full …
the condition of many patients improves with medication, only a minority experience full …
Hypericum perforatum in the treatment of psychiatric and neurodegenerative disorders: Current evidence and potential mechanisms of action
Background Psychiatric disorders are substantially associated with reduced quality of life
and increased mortality. Depression and anxiety are two of the most common psychiatric …
and increased mortality. Depression and anxiety are two of the most common psychiatric …
Pathophysiology of negative symptom dimensions of schizophrenia–current developments and implications for treatment
Negative symptoms of schizophrenia comprise a group of severe symptoms contributing to
high disease burden and poor long-term prognosis. Conceptual work has shown that these …
high disease burden and poor long-term prognosis. Conceptual work has shown that these …