Advances in NK cell production

F Fang, S Xie, M Chen, Y Li, J Yue, J Ma… - Cellular & Molecular …, 2022 - nature.com
Immunotherapy based on natural killer (NK) cells is a promising approach for treating a
variety of cancers. Unlike T cells, NK cells recognize target cells via a major …

Computational design of protein–protein interactions

G Schreiber, SJ Fleishman - Current opinion in structural biology, 2013 - Elsevier
Highlights•The first successfully designed and validated protein–protein interactions were
recently published.•Novel combinations of high-throughput experimental characterization …

Hydrophobic core evolution of major histocompatibility complex class I chain-related protein a for dramatic enhancing binding affinity

W Cai, S Peng, Y Tian, Y Bao, Q Liu, Y Dong… - International Journal of …, 2024 - Elsevier
Interface residues at sites of protein–protein interaction (PPI) are the focus for affinity
optimisation. However, protein hydrophobic cores (HCs) play critical roles and shape the …

Insertable variable fragments of antibodies and modified α1-α2 domains of NKG2D ligands, and non-natural NKG2D ligands that bind non-natural NKG2D receptors

K Landgraf, DP Steiger, T Baron, D Gebhart - US Patent 10,259,858, 2019 - Google Patents
US10259858B2 - Insertable variable fragments of antibodies and modified α1-α2 domains of
NKG2D ligands, and non-natural NKG2D ligands that bind non-natural NKG2D receptors …

食管癌中MICA 的表达及其意义

柳硕岩, 周智锋, 郑庆丰, 李洁羽, 王枫, 叶韵斌 - 中国肿瘤临床, 2013 - cjco.cn
食管癌中MICA的表达及其意义 首页 期刊简介 1.期刊介绍 2.获奖情况 编委会 期刊在线 1.最新
录用 2.优先发表 3.当期目录 4.过刊浏览 视频合辑 在线投稿 1.投稿须知 2.稿约下载 3.版权协议 …

Insertable variable fragments of antibodies and modified A1-A2 domains of NKG2D ligands

K Landgraf, DP Steiger, SR Williams… - US Patent …, 2022 - Google Patents
US11453713B2 - Insertable variable fragments of antibodies and modified A1-A2 domains
of NKG2D ligands - Google Patents US11453713B2 - Insertable variable fragments of …

NKG2D 配体在中晚期食管癌患者术后NK 细胞免疫治疗中的作用

周智锋, 柳硕岩, 郑庆丰, 李洁羽, 陈明水, 王枫… - 中国肿瘤临床, 2013 - cqvip.com
目的: 探讨NKG2D 配体MHC—Ⅰ 类相关分子A (MHCclassI-related moleculesA, MICA)
在中晚期食管癌患者术后化疗联合NK 细胞免疫治疗中的作用. 方法: 福建省肿瘤医院90 …

Measuring Novel Protein-Protein Binding with Surface Plasmon Resonance in the Physical Chemistry Lab

BJ McFarland - Engaging Students in Physical Chemistry, 2018 - ACS Publications
In the laboratory for Survey of Physical Chemistry, students proceeded through a five-week
project in which they measured protein-protein binding. This project engaged the students in …

MICA 在喉癌组织和细胞中的表达及意义

王睿, 王郡甫, 苏庆红, 陈雪梅, 许晓群 - 临床耳鼻咽喉头颈外科杂志, 2016 - cqvip.com
目的: 探讨MICA 在喉癌细胞Hep-2 和喉鳞状细胞癌组织中的表达及意义. 方法: RT—PCR
和Western—blot 方法检测MICAmRNA 和蛋白在喉癌细胞和喉癌组织中的表达情况 …

Online Tools for Teaching Large Laboratory Courses: How the GENI Website Facilitates Authentic Research

BJ McFarland - Teaching and the Internet: The Application of Web …, 2017 - ACS Publications
One educational problem that technology can address is how to facilitate authentic research
experiences in the classroom for large numbers of students. The collaborative online …