Emerging role of trimethylamine-N-oxide (TMAO) in colorectal cancer

R Jalandra, N Dalal, AK Yadav, D Verma… - Applied Microbiology …, 2021 - Springer
Among gut microbiota-derived metabolites, trimethylamine-N-oxide (TMAO) is receiving
increased attention due to its possible role in the carcinogenesis of colorectal cancer (CRC) …

Dietary metabolism, the gut microbiome, and heart failure

WHW Tang, DY Li, SL Hazen - Nature Reviews Cardiology, 2019 - nature.com
Advances in our understanding of how the gut microbiota contributes to human health and
diseases have expanded our insight into how microbial composition and function affect the …

Implication of trimethylamine N-oxide (TMAO) in disease: potential biomarker or new therapeutic target

MH Janeiro, MJ Ramírez, FI Milagro, JA Martínez… - Nutrients, 2018 - mdpi.com
Trimethylamine N-oxide (TMAO) is a molecule generated from choline, betaine, and
carnitine via gut microbial metabolism. The plasma level of TMAO is determined by several …

Bacteroides vulgatus and Bacteroides dorei Reduce Gut Microbial Lipopolysaccharide Production and Inhibit Atherosclerosis

N Yoshida, T Emoto, T Yamashita, H Watanabe… - Circulation, 2018 - Am Heart Assoc
Background: It is increasingly recognized that gut microbiota play a pivotal role in the
development of atherosclerotic cardiovascular disease. Previously, we have reported that …

[HTML][HTML] Trimethylamine N-oxide (TMAO) in human health

P Gatarek, J Kaluzna-Czaplinska - EXCLI journal, 2021 - ncbi.nlm.nih.gov
Due to numerous links between trimethylamine-N-oxide (TMAO) and various disorders and
diseases, this topic is very popular and is often taken up by researchers. TMAO is a low …

Intestinal Microbiota in Cardiovascular Health and Disease: JACC State-of-the-Art Review

WHW Tang, F Bäckhed, U Landmesser… - Journal of the American …, 2019 - jacc.org
Despite major strides in reducing cardiovascular disease (CVD) burden with modification of
classic CVD risk factors, significant residual risks remain. Recent discoveries that linked …

The role of gut microbiota on cholesterol metabolism in atherosclerosis

M Vourakis, G Mayer, G Rousseau - International Journal of Molecular …, 2021 - mdpi.com
Hypercholesterolemia plays a causal role in the development of atherosclerosis and is one
of the main risk factors for cardiovascular disease (CVD), the leading cause of death …

[HTML][HTML] A randomized crossover trial on the effect of plant-based compared with animal-based meat on trimethylamine-N-oxide and cardiovascular disease risk …

A Crimarco, S Springfield, C Petlura, T Streaty… - The American journal of …, 2020 - Elsevier
Background Despite the rising popularity of plant-based alternative meats, there is limited
evidence of the health effects of these products. Objectives We aimed to compare the effect …

The unmapped chemical complexity of our diet

AL Barabási, G Menichetti, J Loscalzo - Nature Food, 2020 - nature.com
Our understanding of how diet affects health is limited to 150 key nutritional components that
are tracked and catalogued by the United States Department of Agriculture and other …

Alterations of the skin and gut microbiome in psoriasis and psoriatic arthritis

I Olejniczak-Staruch, M Ciążyńska… - International journal of …, 2021 - mdpi.com
Numerous scientific studies in recent years have shown significant skin and gut dysbiosis
among patients with psoriasis. A significant decrease in microbiome alpha-diversity …