[HTML][HTML] Natural flavonoids exhibit potent anticancer activity by targeting microRNAs in cancer: A signature step hinting towards clinical perfection
Cancer prevalence and its rate of incidence are constantly rising since the past few
decades. Owing to the toxicity of present-day antineoplastic drugs, it is imperative to explore …
decades. Owing to the toxicity of present-day antineoplastic drugs, it is imperative to explore …
[HTML][HTML] Licorice (Glycyrrhiza glabra L.)-derived phytochemicals target multiple signaling pathways to confer oncopreventive and oncotherapeutic effects
Cancer is a highly lethal disease, and its incidence has rapidly increased worldwide over
the past few decades. Although chemotherapeutics and surgery are widely used in clinical …
the past few decades. Although chemotherapeutics and surgery are widely used in clinical …
[HTML][HTML] PD-L1 overexpression induces STAT signaling and promotes the secretion of pro-angiogenic cytokines in non-small cell lung cancer (NSCLC)
A Cavazzoni, G Digiacomo, F Volta, R Alfieri… - Lung Cancer, 2024 - Elsevier
Background Monoclonal antibodies (ICI) targeting the immune checkpoint PD-1/PD-L1
alone or in combination with chemotherapy have demonstrated relevant benefits and …
alone or in combination with chemotherapy have demonstrated relevant benefits and …
[HTML][HTML] Apigenin loaded lipoid–PLGA–TPGS nanoparticles for colon cancer therapy: Characterization, sustained release, cytotoxicity, and apoptosis pathways
Colon cancer (CC) is one of major causes of mortality and affects the socio-economic status
world-wide. Therefore, developing a novel and efficient delivery system is needed for CC …
world-wide. Therefore, developing a novel and efficient delivery system is needed for CC …
[HTML][HTML] Coding roles of long non-coding RNAs in breast cancer: Emerging molecular diagnostic biomarkers and potential therapeutic targets with special reference to …
Dysregulation of epigenetic mechanisms have been depicted in several pathological
consequence such as cancer. Different modes of epigenetic regulation (DNA methylation …
consequence such as cancer. Different modes of epigenetic regulation (DNA methylation …
[HTML][HTML] Terpenoid-mediated targeting of STAT3 signaling in cancer: an overview of preclinical studies
Cancer has become one of the most multifaceted and widespread illnesses affecting human
health, causing substantial mortality at an alarming rate. After cardiovascular problems, the …
health, causing substantial mortality at an alarming rate. After cardiovascular problems, the …
Anticancer potential of oroxylin A: from mechanistic insight to synergistic perspectives
Oroxylin A (OA), a well-known constituent of the root of Scutellariae plants, has been used in
ethnomedicine already for centuries in treating various neoplastic disorders. However, only …
ethnomedicine already for centuries in treating various neoplastic disorders. However, only …
[HTML][HTML] Survival strategies: How tumor hypoxia microenvironment orchestrates angiogenesis
M Yang, Y Mu, X Yu, D Gao, W Zhang, Y Li, J Liu… - Biomedicine & …, 2024 - Elsevier
During tumor development, the tumor itself must continuously generate new blood vessels to
meet their growth needs while also allowing for tumor invasion and metastasis. One of the …
meet their growth needs while also allowing for tumor invasion and metastasis. One of the …
Lung cancer treatment potential and limits associated with the STAT family of transcription factors
P Faida, MKI Attiogbe, U Majeed, J Zhao, L Qu, D Fan - Cellular Signalling, 2023 - Elsevier
Lung cancer is one of the mortal cancers and the leading cause of cancer-related mortality,
with a cancer survival rate of fewer than 5% in developing nations. This low survival rate can …
with a cancer survival rate of fewer than 5% in developing nations. This low survival rate can …
Recent Insights into the Roles of PEST‐Containing Nuclear Protein
S Guo, R Ding, Q Zhao, X Wang, S Lv, XY Ji - Molecular Biotechnology, 2024 - Springer
PEST-containing nuclear protein (PCNP), a short-lived small nuclear protein with 178 amino
acids, is a nuclear protein containing two PEST sequences. PCNP is highly expressed in …
acids, is a nuclear protein containing two PEST sequences. PCNP is highly expressed in …