Nociception is the process whereby primary afferent nerve fibers of the somatosensory
system detect noxious stimuli. Pungent irritants from pepper, mint, and mustard plants have …

In recent years, considerable progress has been achieved in the comprehension of the
profound effects of pheromones on reproductive physiology and behavior. Pheromones …

Transient receptor potential (TRP) channels are a widely expressed family of 28
evolutionarily conserved cationic ion channels that operate as primary detectors of chemical …

Diacylglycerol (DAG) has unique functions as a basic component of membranes, an
intermediate in lipid metabolism and a key element in lipid-mediated signaling. In …

Intrinsically photosensitive retinal ganglion cells (ipRGCs) are photoreceptors of the
mammalian eye that drive pupillary responses, synchronization of circadian rhythms, and …

Transient receptor potential (TRP) channels are essential components of biological sensors
that detect changes in the environment in response to a myriad of stimuli. A major difficulty in …

There is a rapidly growing interest in the family of transient receptor potential (TRP)
channels because TRP channels are not only important for many sensory systems, but they …

The transient receptor potential (TRP) ion channel family was the last major ion channel
family to be discovered. The prototypical member (dTRP) was identified by a forward genetic …

Cancer is the second most common cause of death in western countries. It is therefore of
fundamental importance to improve the treatment of patients with malignant tumors. This …

A small number (< 2%) of mammalian retinal ganglion cells express the photopigment
melanopsin and are intrinsically photosensitive (ipRGCs). Light depolarizes ipRGCs and …