Mechanisms and regulation of protein synthesis in mitochondria

E Kummer, N Ban - Nature Reviews Molecular Cell Biology, 2021 - nature.com
Mitochondria are cellular organelles responsible for generation of chemical energy in the
process called oxidative phosphorylation. They originate from a bacterial ancestor and …

[HTML][HTML] Herbal medicine derived carbon dots: synthesis and applications in therapeutics, bioimaging and sensing

WK Luo, LL Zhang, ZY Yang, XH Guo, Y Wu… - Journal of …, 2021 - Springer
Since the number of raw material selections for the synthesis of carbon dots (CDs) has
grown extensively, herbal medicine as a precursor receives an increasing amount of …

Structure and function of the mitochondrial ribosome

BJ Greber, N Ban - Annual review of biochemistry, 2016 - annualreviews.org
Mitochondrial ribosomes (mitoribosomes) perform protein synthesis inside mitochondria, the
organelles responsible for energy conversion and adenosine triphosphate production in …

[HTML][HTML] Regulation of mRNA translation in neurons—a matter of life and death

M Kapur, CE Monaghan, SL Ackerman - Neuron, 2017 - cell.com
Dynamic regulation of mRNA translation initiation and elongation is essential for the survival
and function of neural cells. Global reductions in translation initiation resulting from …

[HTML][HTML] Recent advances in mitochondrial aminoacyl-tRNA synthetases and disease

M Sissler, LE González-Serrano, E Westhof - Trends in molecular medicine, 2017 - cell.com
Dysfunctions in mitochondria–the powerhouses of the cell–lead to several human
pathologies. Because mitochondria integrate nuclear and mitochondrial genetic systems …

Mitochondrial ribosomes in cancer

HJ Kim, P Maiti, A Barrientos - Seminars in cancer biology, 2017 - Elsevier
Mitochondria play fundamental roles in the regulation of life and death of eukaryotic cells.
They mediate aerobic energy conversion through the oxidative phosphorylation (OXPHOS) …

Architecture of the large subunit of the mammalian mitochondrial ribosome

BJ Greber, D Boehringer, A Leitner, P Bieri… - Nature, 2014 - nature.com
Mitochondrial ribosomes synthesize a number of highly hydrophobic proteins encoded on
the genome of mitochondria, the organelles in eukaryotic cells that are responsible for …

[HTML][HTML] ELAC2 mutations cause a mitochondrial RNA processing defect associated with hypertrophic cardiomyopathy

TB Haack, R Kopajtich, P Freisinger, T Wieland… - The American Journal of …, 2013 - cell.com
The human mitochondrial genome encodes RNA components of its own translational
machinery to produce the 13 mitochondrial-encoded subunits of the respiratory chain …

Interplay of mitochondrial metabolism and microRNAs

J Geiger, LT Dalgaard - Cellular and Molecular Life Sciences, 2017 - Springer
Mitochondria are important organelles in cellular metabolism. Several crucial metabolic
pathways such as the energy producing electron transport chain or the tricarboxylic acid …

[HTML][HTML] Stepwise maturation of the peptidyl transferase region of human mitoribosomes

T Lenarčič, M Jaskolowski, M Leibundgut… - Nature …, 2021 - nature.com
Mitochondrial ribosomes are specialized for the synthesis of membrane proteins responsible
for oxidative phosphorylation. Mammalian mitoribosomes have diverged considerably from …