In-depth single-cell analysis of translation-competent HIV-1 reservoirs identifies cellular sources of plasma viremia
B Cole, L Lambrechts, P Gantner, Y Noppe… - Nature …, 2021 - nature.com
Clonal expansion of HIV-infected cells contributes to the long-term persistence of the HIV
reservoir in ART-suppressed individuals. However, the contribution from cell clones that …
reservoir in ART-suppressed individuals. However, the contribution from cell clones that …
Novel role of UHRF1 in the epigenetic repression of the latent HIV-1
R Verdikt, M Bendoumou, S Bouchat, L Nestola… - …, 2022 - thelancet.com
Background The multiplicity, heterogeneity, and dynamic nature of human
immunodeficiency virus type-1 (HIV-1) latency mechanisms are reflected in the current lack …
immunodeficiency virus type-1 (HIV-1) latency mechanisms are reflected in the current lack …
Epigenetic landscape in the kick-and-kill therapeutic vaccine BCN02 clinical trial is associated with antiretroviral treatment interruption (ATI) outcome
B Oriol-Tordera, A Esteve-Codina, M Berdasco… - …, 2022 - thelancet.com
Background The BCN02-trial combined therapeutic vaccination with a viral latency reversing
agent (romidepsin, RMD) in HIV-1-infected individuals and included a monitored …
agent (romidepsin, RMD) in HIV-1-infected individuals and included a monitored …
[PDF][PDF] HIV cure trial mergers: spotlighting the epigenetics of latency reversal
PW Denton - EBioMedicine, 2022 - thelancet.com
Developing a scalable approach to cure HIV-1 infection remains a high priority. 1 In recent
years, pivotal advances have pushed the field toward such a cure À which could be realized …
years, pivotal advances have pushed the field toward such a cure À which could be realized …
Novel role of UHRF1 in the epigenetic repression of the latent HIV-1.
M Bendoumou, S Bouchat, L Nestola, A Pasternak… - 2022 - escholarship.org
BACKGROUND: The multiplicity, heterogeneity, and dynamic nature of human
immunodeficiency virus type-1 (HIV-1) latency mechanisms are reflected in the current lack …
immunodeficiency virus type-1 (HIV-1) latency mechanisms are reflected in the current lack …