Astrocytes, an integral component of the central nervous system (CNS), contribute to the
maintenance of physiological homeostasis through their roles in synaptic function, K+ …

Amyotrophic lateral sclerosis (ALS) is a devastating motor neuron disease for which there is
currently no robust therapy. Recent progress in understanding ALS disease mechanisms …

Ischemic brain injuries are common diseases with high morbidity, disability, and mortality
rates, which have significant impacts on human health and life. Microglia are resident cells …

Astrocytes are the most widespread and heterogeneous glial cells in the central nervous
system and key regulators for brain development. They are capable of receiving …

In multiple sclerosis (MS) patients with a progressive form of the disease, spinal cord (SC)
functions slowly deteriorate beyond age 40. We previously showed that in the SC of these …

Encephalopathy of prematurity (EoP) is a major cause of morbidity in preterm neonates,
causing neurodevelopmental adversities that can lead to lifelong impairments. Preterm birth …

Amyotrophic lateral sclerosis (ALS) is one of the most common neurodegenerative diseases,
causing degeneration of both upper and lower motor neurons in the central nervous system …

Background Neuropathic pain (NP) is known to be highly correlated with microglial
polarization, of which the regulatory mechanism remains to be elucidated. Here, the aim of …

Abstract Amyotrophic Lateral Sclerosis (ALS) belongs to the family of neurodegenerative
disorders and is classified as fronto-temporal dementia (FTD), progressive muscular …

This commentary focuses on the emerging intersection between BMP/TGF‐β signaling roles
in nervous system function and the amyotrophic lateral sclerosis (ALS) disease state. Future …