Current two‐dimensional electrophoresis technology for proteomics

A Görg, W Weiss, MJ Dunn - Proteomics, 2004 - Wiley Online Library
Abstract Two‐dimensional gel electrophoresis (2‐DE) with immobilized pH gradients (IPGs)
combined with protein identification by mass spectrometry (MS) is currently the workhorse …

Proteomics of integral membrane proteins theory and application

AE Speers, CC Wu - Chemical reviews, 2007 - ACS Publications
Integral membrane proteins (IMPs) lie at the critical junctions between intracellular
compartments and cells and their environment. As such, IMPs are in a unique position to …

Divergent evolution of temozolomide resistance in glioblastoma stem cells is reflected in extracellular vesicles and coupled with radiosensitization

D Garnier, B Meehan, T Kislinger, P Daniel… - Neuro …, 2018 - academic.oup.com
Background Glioblastoma (GBM) is almost invariably fatal due to failure of standard therapy.
The relapse of GBM following surgery, radiation, and systemic temozolomide (TMZ) is …

In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome

A Sinha, V Ignatchenko, A Ignatchenko… - Biochemical and …, 2014 - Elsevier
Molecular communication between cancer cells and its stromal microenvironment is a key
factor for cancer progression. Alongside classic secretory pathways, it has recently been …

Development and evaluation of a micro-and nanoscale proteomic sample preparation method

H Wang, WJ Qian, HM Mottaz… - Journal of proteome …, 2005 - ACS Publications
Challenges associated with the efficient and effective preparation of micro-and nanoscale
(micro-and nanogram) clinical specimens for proteomic applications include the unmitigated …

[图书][B] Handbook of Listeria monocytogenes

D Liu - 2008 - taylorfrancis.com
Once feared as a deadly intracellular bacterium with the extraordinary capacity to survive a
wide array of arduous external stressors, Listeria monocytogenes is increasingly recognized …

Multicomponent Moraxella catarrhalis outer membrane vesicles induce an inflammatory response and are internalized by human epithelial cells

V Schaar, SPW De Vries… - Cellular …, 2011 - Wiley Online Library
Moraxella catarrhalis is an emerging human respiratory pathogen in patients with chronic
obstructive pulmonary disease (COPD) and in children with acute otitis media. The specific …

Trifluoroethanol and the behavior of a tardigrade desiccation‐tolerance protein

S Wang, J Eicher, GJ Pielak - Protein Science, 2023 - Wiley Online Library
Abstract The cosolvent 2, 2, 2‐trifluoroethanol (TFE) is often used to mimic protein
desiccation. We assessed the effects of TFE on cytosolic abundant heat soluble protein D …

Adapted tolerance to benzalkonium chloride in Escherichia coli K-12 studied by transcriptome and proteome analyses

E Bore, M Hebraud, I Chafsey, C Chambon… - …, 2007 - microbiologyresearch.org
Benzalkonium chloride (BC) is a commonly used disinfectant and preservative. This study
describes changes in expression level at the transcriptomic and proteomic level for …

Cell-surface proteomics for the identification of novel therapeutic targets in cancer

L Kuhlmann, E Cummins, I Samudio… - Expert review of …, 2018 - Taylor & Francis
Introduction: Cancer is the second most common cause of death worldwide and its
heterogeneity complicates therapy. Standard cytotoxic regiments disrupt rapidly dividing …