The fungal cell wall: structure, biosynthesis, and function
The molecular composition of the cell wall is critical for the biology and ecology of each
fungal species. Fungal walls are composed of matrix components that are embedded and …
fungal species. Fungal walls are composed of matrix components that are embedded and …
Basic principles of the virulence of Cryptococcus
O Zaragoza - Virulence, 2019 - Taylor & Francis
Among fungal pathogens, Cryptococcus neoformans has gained great importance among
the scientific community of several reasons. This fungus is the causative agent of …
the scientific community of several reasons. This fungus is the causative agent of …
The capsule of the fungal pathogen Cryptococcus neoformans
The capsule of the fungal pathogen Cryptococcus neoformans has been studied extensively
in recent decades and a large body of information is now available to the scientific …
in recent decades and a large body of information is now available to the scientific …
The myriad roles of cyclic AMP in microbial pathogens: from signal to sword
KA McDonough, A Rodriguez - Nature Reviews Microbiology, 2012 - nature.com
All organisms must sense and respond to their external environments, and this signal
transduction often involves second messengers such as cyclic nucleotides. One such …
transduction often involves second messengers such as cyclic nucleotides. One such …
Expanding fungal pathogenesis: Cryptococcus breaks out of the opportunistic box
JW Kronstad, R Attarian, B Cadieux, J Choi… - Nature reviews …, 2011 - nature.com
Cryptococcus neoformans is generally considered to be an opportunistic fungal pathogen
because of its tendency to infect immunocompromised individuals, particularly those …
because of its tendency to infect immunocompromised individuals, particularly those …
Coevolution of morphology and virulence in Candida species
DS Thompson, PL Carlisle, D Kadosh - Eukaryotic cell, 2011 - Am Soc Microbiol
Many of the major human fungal pathogens are known to undergo morphological changes,
which in certain cases are associated with virulence. Although there has been an intense …
which in certain cases are associated with virulence. Although there has been an intense …
Population genomics and the evolution of virulence in the fungal pathogen Cryptococcus neoformans
CA Desjardins, C Giamberardino, SM Sykes… - Genome …, 2017 - genome.cshlp.org
Cryptococcus neoformans is an opportunistic fungal pathogen that causes approximately
625,000 deaths per year from nervous system infections. Here, we leveraged a unique …
625,000 deaths per year from nervous system infections. Here, we leveraged a unique …
Our paths might cross: the role of the fungal cell wall integrity pathway in stress response and cross talk with other stress response pathways
BB Fuchs, E Mylonakis - Eukaryotic cell, 2009 - Am Soc Microbiol
Fungi occupy diverse environments and are subjected to many extreme conditions. Among
the stressful conditions faced by fungi are pH changes, osmotic changes, thermal changes …
the stressful conditions faced by fungi are pH changes, osmotic changes, thermal changes …
Components of the calcium-calcineurin signaling pathway in fungal cells and their potential as antifungal targets
S Liu, Y Hou, W Liu, C Lu, W Wang, S Sun - Eukaryotic cell, 2015 - Am Soc Microbiol
In recent years, the emergence of fungal resistance has become frequent, partly due to the
widespread clinical use of fluconazole, which is minimally toxic and effective in the …
widespread clinical use of fluconazole, which is minimally toxic and effective in the …
Calcineurin Plays Key Roles in the Dimorphic Transition and Virulence of the Human Pathogenic Zygomycete Mucor circinelloides
Many pathogenic fungi are dimorphic and switch between yeast and filamentous states. This
switch alters host-microbe interactions and is critical for pathogenicity. However, in …
switch alters host-microbe interactions and is critical for pathogenicity. However, in …