The onset of cardiomyopathy is a common feature in sepsis, with relevant effects on its
pathophysiology and clinical care. Septic cardiomyopathy is characterized by reduced left …

Septic cardiomyopathy (SCM) is a complication that is sepsis-associated cardiovascular
failure. In the last few decades, there is progress in diagnosis and treatment despite the lack …

Accumulating evidence has indicated that activation of microglia and neuroinflammation
reaction play a prominent role in Alzheimer's disease (AD). Inhibition of toll-like receptor 4 …

FK506 binding (FKBP) proteins are part of the highly conserved immunophilin family and its
members have fundamental roles in the regulation of signalling pathways involved in …

Background: Mutations in tafazzin (TAZ), a gene required for biogenesis of cardiolipin, the
signature phospholipid of the inner mitochondrial membrane, causes Barth syndrome …

Diabetes mellitus (DM) is associated with increased arrhythmia. Type 2 DM (T2DM) mice
showed prolonged QT interval and increased ventricular arrhythmic inducibility …

Toddalolactone (TA-8) is a main compound isolated from Toddalia asiatica (L.) Lam., and its
anti-inflammatory activity and anti-inflammatory mechanism are less studied. In the present …

The pathogenesis of viral myocarditis includes both the direct damage mediated by viral
infection and the indirect lesion resulted from host immune responses. Myocarditis can …

Cardiovascular remodeling occurs in cardiomyocytes, collagen meshes, and vascular beds
in the progress of cardiac insufficiency caused by a variety of cardiac diseases such as …

Irisin plays a protective effect in acute and chronic myocardial damage, but its role in septic
cardiomyopathy is unclear. The aim of our study was to explore the in vivo and in vitro effects …