Strain engineering of Saccharomyces cerevisiae for enhanced xylose metabolism

SR Kim, YC Park, YS Jin, JH Seo - Biotechnology advances, 2013 - Elsevier
Efficient and rapid fermentation of all sugars present in cellulosic hydrolysates is essential
for economic conversion of renewable biomass into fuels and chemicals. Xylose is one of …

Simultaneous co-fermentation of mixed sugars: a promising strategy for producing cellulosic ethanol

SR Kim, SJ Ha, N Wei, EJ Oh, YS Jin - Trends in biotechnology, 2012 - cell.com
The lack of microbial strains capable of fermenting all sugars prevalent in plant cell wall
hydrolyzates to ethanol is a major challenge. Although naturally existing or engineered …

Big data mining, rational modification, and ancestral sequence reconstruction inferred multiple xylose isomerases for biorefinery

S Chen, Z Xu, B Ding, Y Zhang, S Liu, C Cai, M Li… - Science …, 2023 - science.org
The isomerization of xylose to xylulose is considered the most promising approach to initiate
xylose bioconversion. Here, phylogeny-guided big data mining, rational modification, and …

Development of a D-xylose fermenting and inhibitor tolerant industrial Saccharomyces cerevisiae strain with high performance in lignocellulose hydrolysates using …

MM Demeke, H Dietz, Y Li, MR Foulquié-Moreno… - Biotechnology for …, 2013 - Springer
Background The production of bioethanol from lignocellulose hydrolysates requires a
robust, D-xylose-fermenting and inhibitor-tolerant microorganism as catalyst. The purpose of …

Xylose fermentation efficiency of industrial Saccharomyces cerevisiae yeast with separate or combined xylose reductase/xylitol dehydrogenase and xylose isomerase …

JT Cunha, PO Soares, A Romaní, JM Thevelein… - Biotechnology for …, 2019 - Springer
Background Xylose isomerase (XI) and xylose reductase/xylitol dehydrogenase (XR/XDH)
pathways have been extensively used to confer xylose assimilation capacity to …

Controlling heterologous gene expression in yeast cell factories on different carbon substrates and across the diauxic shift: a comparison of yeast promoter activities

B Peng, TC Williams, M Henry, LK Nielsen… - Microbial cell …, 2015 - Springer
Background Predictable control of gene expression is necessary for the rational design and
optimization of cell factories. In the yeast Saccharomyces cerevisiae, the promoter is one of …

Rational and Evolutionary Engineering Approaches Uncover a Small Set of Genetic Changes Efficient for Rapid Xylose Fermentation in Saccharomyces cerevisiae

SR Kim, JM Skerker, W Kang, A Lesmana, N Wei… - PloS one, 2013 - journals.plos.org
Economic bioconversion of plant cell wall hydrolysates into fuels and chemicals has been
hampered mainly due to the inability of microorganisms to efficiently co-ferment pentose and …

Engineered Saccharomyces cerevisiae for lignocellulosic valorization: a review and perspectives on bioethanol production

JT Cunha, PO Soares, SL Baptista, CE Costa… - …, 2020 - Taylor & Francis
The biorefinery concept, consisting in using renewable biomass with economical and
energy goals, appeared in response to the ongoing exhaustion of fossil reserves. Bioethanol …

Exploring yeast diversity to produce lipid-based biofuels from agro-forestry and industrial organic residues

MN Mota, P Múgica, I Sá-Correia - Journal of Fungi, 2022 - mdpi.com
Exploration of yeast diversity for the sustainable production of biofuels, in particular
biodiesel, is gaining momentum in recent years. However, sustainable, and economically …

Engineering of Saccharomyces cerevisiae for the efficient co-utilization of glucose and xylose

J Hou, C Qiu, Y Shen, H Li, X Bao - FEMS yeast research, 2017 - academic.oup.com
The rapid co-fermentation of both glucose and xylose is important for the efficient conversion
of lignocellulose biomass into fuels and chemicals. Saccharomyces cerevisiae is considered …