Background Some studies have reported that exposure to depression increases the risk of
erectile dysfunction (ED), whereas others have observed no association. Moreover …

Sexual dysfunction (SD) is a disorder of sexual behavior and sexual sensation that appears
as an abnormality or absence of sexual psychology and physiological reaction. It is a …

Introduction Strategies of harm reduction (HR) include policies and community-based
measures aimed to reduce the risk of self-harm while continuing potentially hazardous …

Background Substance use may affect sexual functioning in both men and women.
Comorbid sexual dysfunction adds to the clinical burden of substance use disorders (SUD) …

Opioids are pivotal therapeutics in the management of escalated chronic pain (moderate–
severe). In the last two decades, the increased prescription rate and the prolonged usage of …

Background Opioid analgesics have been widely used to relieve chronic pain conditions;
however, a connection between opioid analgesic administration and increased susceptibility …

Background While methadone maintenance therapy (MMT) in patients with opioid use
disorder (OUD) decreases the risk of substance use relapses and criminal and risky sexual …

Background and Objectives Compliance and maintenance of abstinence is a major issue in
substance use disorders. Adverse effects of opioid maintenance treatments (OMT) include …

Methadone is largely recognized as an effective treatment for opiate-dependent patients;
however, it causes reduced brain dopaminergic action resulting in significant sexual …

Background Some patients with opioid use disorder (OUD) are treated with methadone
maintenance therapy (MMT). However, as with opioids, methadone has major side-effects; …