Rats and mice are used for studying neuronal circuits underlying recognition memory due to
their ability to spontaneously remember the occurrence of an object, its place and an …

The aims of the paper are to update Rolls' quantitative computational theory of hippocampal
function and the predictions it makes about the different subregions (dentate gyrus, CA3 and …

Pericytes play a key role in the development of cerebral microcirculation. The exact role of
pericytes in the neurovascular unit in the adult brain and during brain aging remains …

This unit is designed to provide sufficient instruction for the setup and execution of tests for
object location and object recognition in adult mice. This task is ideally suited for the study of …

In Alzheimer disease (AD), amyloid β peptide (Aβ) accumulates in plaques in the brain.
Receptor for advanced glycation end products (RAGE) mediates Aβ-induced perturbations …

Long-term depression (LTD) in the CNS has been the subject of intense investigation as a
process that may be involved in learning and memory and in various pathological …

The ability to recognize a previously experienced stimulus is supported by two processes:
recollection of the stimulus in the context of other information associated with the …

Elucidating the role of the rodent hippocampus in object recognition memory is critical for
establishing the appropriateness of rodents as models of human memory and for their use in …

Rats and mice are attracted by novel objects. They readily approach novel objects and
explore them with their vibrissae, nose and forepaws. It is assumed that such a single …

Here we describe a model of medial temporal lobe organization in which parallel “what” and
“where” processing streams converge within the hippocampus to represent events in the …