[HTML][HTML] Recurrent urinary tract infection: a mystery in search of better model systems

BO Murray, C Flores, C Williams… - Frontiers in cellular …, 2021 - frontiersin.org
Urinary tract infections (UTIs) are among the most common infectious diseases worldwide
but are significantly understudied. Uropathogenic E. coli (UPEC) accounts for a significant …

[HTML][HTML] The urinary microbiome and biological therapeutics: Novel therapies for urinary tract infections

C Kenneally, CP Murphy, RD Sleator… - Microbiological …, 2022 - Elsevier
The discovery of microbial communities in the urinary tract (the urobiome) has fundamentally
altered the previous doctrine regarding urine sterility and associated urinary disorders …

Rapid growth and metabolism of uropathogenic Escherichia coli in relation to urine composition

L Reitzer, P Zimmern - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Uropathogenic Escherichia coli (UPEC) strains cause a majority of urinary tract infections
(UTIs). Since UPEC strains can become antibiotic resistant, adjunct or alternate therapies …

[HTML][HTML] Phylogenetic classification and functional review of autotransporters

KR Clarke, L Hor, A Pilapitiya, J Luirink… - Frontiers in …, 2022 - frontiersin.org
Autotransporters are the core component of a molecular nano-machine that delivers cargo
proteins across the outer membrane of Gram-negative bacteria. Part of the type V secretion …

Characterization of water treatment-resistant and multidrug-resistant urinary pathogenic Escherichia coli in treated wastewater

S Zhi, P Stothard, G Banting, C Scott, K Huntley, K Ryu… - Water research, 2020 - Elsevier
A growing body of evidence has demonstrated that extraintestinal pathogenic E. coli
(ExPEC), such as the urinary pathogenic E. coli (UPEC), are common constituents of treated …

[HTML][HTML] Whole Genome Sequencing for Genomics-Guided Investigations of Escherichia coli O157:H7 Outbreaks

B Rusconi, F Sanjar, SSK Koenig… - Frontiers in …, 2016 - frontiersin.org
Multi isolate whole genome sequencing (WGS) and typing for outbreak investigations has
become a reality in the post-genomics era. We applied this technology to strains from …

Differential Afa/Dr fimbriae expression in the multidrug-resistant Escherichia coli ST131 clone

L Alvarez-Fraga, MD Phan, KGK Goh, NTK Nhu… - MBio, 2022 - Am Soc Microbiol
Many antibiotic resistant uropathogenic Escherichia coli (UPEC) strains belong to clones
defined by their multilocus sequence type (ST), with ST131 being the most dominant …

pBuzz: a cryptic rolling-circle plasmid from a commensal Escherichia coli has two inversely oriented oriTs and is mobilised by a B/O plasmid

RA Moran, RM Hall - Plasmid, 2019 - Elsevier
Ampicillin, streptomycin and sulphamethoxazole resistant commensal E. coli 838-3B
contains five plasmids that range in size from> 90 kb to< 2 kb. The resistance genes bla TEM …

Comparative Pathogenomics of Escherichia coli: Polyvalent Vaccine Target Identification through Virulome Analysis

JR Clark, AM Maresso - Infection and Immunity, 2021 - Am Soc Microbiol
Comparative genomics of bacterial pathogens has been useful for revealing potential
virulence factors. Escherichia coli is a significant cause of human morbidity and mortality …

[HTML][HTML] Distribution of virulence factors, antimicrobial resistance genes and phylogenetic relatedness among Shiga toxin-producing Escherichia coli serogroup O91 …

M Nüesch-Inderbinen, MJA Stevens, N Cernela… - International Journal of …, 2021 - Elsevier
Shiga toxin-producing Escherichia coli (STEC) belonging to the serogroup O91 are among
the most common non-O157 STEC serogroups associated with human illness in Europe …