CRISPRi functional genomics in bacteria and its application to medical and industrial research
AL Enright, WJ Heelan, RD Ward… - … and Molecular Biology …, 2024 - Am Soc Microbiol
Functional genomics is the use of systematic gene perturbation approaches to determine the
contributions of genes under conditions of interest. Although functional genomic strategies …
contributions of genes under conditions of interest. Although functional genomic strategies …
Mobile-CRISPRi as a powerful tool for modulating Vibrio gene expression
LJ Geyman, MP Tanner… - Applied and …, 2024 - Am Soc Microbiol
ABSTRACT CRISPRi (Clustered Regularly Interspaced Palindromic Repeats interference) is
a gene knockdown method that uses a deactivated Cas9 protein (dCas9) that binds a …
a gene knockdown method that uses a deactivated Cas9 protein (dCas9) that binds a …
Lipid membrane remodeling and metabolic response during isobutanol and ethanol exposure in Zymomonas mobilis
J Rivera Vazquez, E Trujillo, J Williams, F She… - … for Biofuels and …, 2024 - Springer
Background Recent engineering efforts have targeted the ethanologenic bacterium
Zymomonas mobilis for isobutanol production. However, significant hurdles remain due this …
Zymomonas mobilis for isobutanol production. However, significant hurdles remain due this …
[HTML][HTML] A Targeted Genome-scale Overexpression Platform for Proteobacteria
Targeted, genome-scale gene perturbation screens using Clustered Regularly Interspaced
Short Palindromic Repeats interference (CRISPRi) and activation (CRISPRa) have …
Short Palindromic Repeats interference (CRISPRi) and activation (CRISPRa) have …