Subsets of regulatory T cells and their roles in allergy

H Zhang, H Kong, X Zeng, L Guo, X Sun… - Journal of translational …, 2014 - Springer
In recent years, it is recognized that acquired immunity is controlled by regulatory T cell
(Treg). Since fundamental pathophysiological changes of allergy are mainly caused by …

Regulatory B cells in anti-tumor immunity

Y Zhang, N Gallastegui… - International …, 2015 - academic.oup.com
Advances in understanding of the immune microenvironment have highlighted the role of
immunosuppressive T cell, myeloid, dendritic and monocytic sub-populations in inhibition of …

The immune potential and immunopathology of cytokine-producing B cell subsets: a comprehensive review

Y Bao, X Cao - Journal of autoimmunity, 2014 - Elsevier
B lymphocytes are generally recognized for their potential to mediate humoral immunity by
producing different antibody isotypes and being involved in opsonization and complement …

Helminth‐induced CD19+CD23hi B cells modulate experimental allergic and autoimmune inflammation

MS Wilson, MD Taylor, MT O'Gorman… - European journal of …, 2010 - Wiley Online Library
Numerous population studies and experimental models suggest that helminth infections can
ameliorate immuno‐inflammatory disorders such as asthma and autoimmunity …

High‐dose bee venom exposure induces similar tolerogenic B‐cell responses in allergic patients and healthy beekeepers

T Boonpiyathad, N Meyer, M Moniuszko… - Allergy, 2017 - Wiley Online Library
Background The involvement of B cells in allergen tolerance induction remains largely
unexplored. This study investigates the role of B cells in this process, by comparing B‐cell …

Multiple mechanisms of immune suppression by B lymphocytes

MW Klinker, SK Lundy - Molecular medicine, 2012 - Springer
Suppression of the immune system after the resolution of infection or inflammation is an
important process that limits immune-mediated pathogenesis and autoimmunity. Several …

IL-10-independent regulatory B-cell subsets and mechanisms of action

A Ray, L Wang, BN Dittel - International immunology, 2015 - academic.oup.com
Although classically B cells are known to play important roles in immune protection via
humoral immunity, recently their regulatory mechanisms have been best appreciated in the …

Regulatory B cells and allergic diseases

G Noh, JH Lee - Allergy, asthma & immunology research, 2011 - synapse.koreamed.org
B cells are generally considered to positively regulate immune responses by producing
antigen-specific antibodies. B cells are classified into classical CD5-conventional B cells …

Regulatory B cells from hilar lymph nodes of tolerant mice in a murine model of allergic airway disease are CD5+, express TGF-β, and co-localize with CD4+ Foxp3+ T …

P Natarajan, A Singh, JT McNamara, ER Secor… - Mucosal …, 2012 - nature.com
In a biphasic, ovalbumin (OVA)-induced murine asthma model where allergic airway
disease is followed by resolution and the development of local inhalational tolerance (LIT) …

The role of B lymphocytes in the progression from autoimmunity to autoimmune disease

GF Salinas, F Braza, S Brouard, PP Tak, D Baeten - Clinical immunology, 2013 - Elsevier
Autoimmunity, defined as the presence of autoreactive T and/or B lymphocytes in the
periphery, is a frequent and probably even physiological condition. It is mainly caused by the …