Abundant genetic variation+ strong selection= multivariate genetic constraints: a geometric view of adaptation

B Walsh, MW Blows - Annual review of ecology, evolution, and …, 2009 - annualreviews.org
Evolutionary biology has struggled to explain the coexistence of two basic observations:
Genetic variation is found in almost all traits in the presence of strong natural and sexual …

Evolutionary constraint and ecological consequences

DJ Futuyma - Evolution, 2010 - academic.oup.com
One of the most important shifts in evolutionary biology in the past 50 years is an increased
recognition of sluggish evolution and failures to adapt, which seem paradoxical in view of …

Estimating nonlinear selection gradients using quadratic regression coefficients: double or nothing?

JR Stinchcombe, AF Agrawal, PA Hohenlohe… - …, 2008 - academic.oup.com
The use of regression analysis has been instrumental in allowing evolutionary biologists to
estimate the strength and mode of natural selection. Although directional and correlational …

Patterns of quantitative genetic variation in multiple dimensions

M Kirkpatrick - Genetica, 2009 - Springer
A fundamental question for both evolutionary biologists and breeders is the extent to which
genetic correlations limit the ability of populations to respond to selection. Here I view this …

[图书][B] The evolution of insect mating systems

DM Shuker, LW Simmons - 2014 - books.google.com
Insects display a staggering diversity of mating and social behaviours. Studying these
systems provides insights into a wide range of evolutionary and behavioural questions, such …

[HTML][HTML] Comparing G: multivariate analysis of genetic variation in multiple populations

JD Aguirre, E Hine, K McGuigan, MW Blows - Heredity, 2014 - nature.com
The additive genetic variance–covariance matrix (G) summarizes the multivariate genetic
relationships among a set of traits. The geometry of G describes the distribution of …

The contribution of selection and genetic constraints to phenotypic divergence

SF Chenoweth, HD Rundle… - The American …, 2010 - journals.uchicago.edu
Although divergent natural selection is common in nature, the extent to which genetic
constraints bias evolutionary trajectories in its presence remains largely unknown. Here we …

Numbering the hairs on our heads: the shared challenge and promise of phenomics

D Houle - Proceedings of the National Academy of …, 2010 - National Acad Sciences
Evolution and medicine share a dependence on the genotype–phenotype map. Although
genotypes exist and are inherited in a discrete space convenient for many sorts of analyses …

Cryptic genetic variation and body size evolution in threespine stickleback

K McGuigan, N Nishimura, M Currey, D Hurwit… - …, 2011 - academic.oup.com
The role of environment as a selective agent is well‐established. Environment might also
influence evolution by altering the expression of genetic variation associated with …

A test of the hypothesis that correlational selection generates genetic correlations

DA Roff, DJ Fairbairn - Evolution, 2012 - academic.oup.com
Abstract Theory predicts that correlational selection on two traits will cause the major axis of
the bivariate G matrix to orient itself in the same direction as the correlational selection …