The anti-inflammatory properties of phytochemicals and their effects on epigenetic mechanisms involved in TLR4/NF-κB-mediated inflammation

HA Saleh, MH Yousef, A Abdelnaser - Frontiers in immunology, 2021 - frontiersin.org
Innate immune response induces positive inflammatory transducers and regulators in order
to attack pathogens, while simultaneously negative signaling regulators are transcribed to …

Flavones: from biosynthesis to health benefits

N Jiang, AI Doseff, E Grotewold - Plants, 2016 - mdpi.com
Flavones correspond to a flavonoid subgroup that is widely distributed in the plants, and
which can be synthesized by different pathways, depending on whether they contain C-or O …

Influence of the Mediterranean diet on healthy aging

MC Andreo-López, V Contreras-Bolívar… - International Journal of …, 2023 - mdpi.com
The life expectancy of the global population has increased. Aging is a natural physiological
process that poses major challenges in an increasingly long-lived and frail population …

CD38 is robustly induced in human macrophages and monocytes in inflammatory conditions

SA Amici, NA Young, J Narvaez-Miranda… - Frontiers in …, 2018 - frontiersin.org
Macrophages and their monocyte precursors mediate innate immune responses and can
promote a spectrum of phenotypes from pro-inflammatory to pro-resolving. Currently, there …

Non-coding RNAs and exosomes: their role in the pathogenesis of sepsis

SMR Hashemian, MH Pourhanifeh, S Fadaei… - … Therapy-Nucleic Acids, 2020 - cell.com
Sepsis is characterized as an uncontrolled host response to infection, and it represents a
serious health challenge, causing excess mortality and morbidity worldwide. The discovery …

[HTML][HTML] Phenolic compounds in Lycium berry: Composition, health benefits and industrial applications

Y Jiang, Z Fang, W Leonard, P Zhang - Journal of Functional Foods, 2021 - Elsevier
This review provides a comprehensive summary of phenolic compounds in Lycium berry,
focusing on their composition, functionalities, potential health benefits, industrial …

Apigenin: A current review on its beneficial biological activities

X Zhou, F Wang, R Zhou, X Song… - Journal of Food …, 2017 - Wiley Online Library
Abstract Apigenin, identified as 4′, 5, 7‐trihydroxyflavone, is a natural flavonoid compound
present in a variety of fruits, vegetables, functional foods, and medicinal plants. Many studies …

Anti-inflammatory mechanisms of dietary flavones: tapping into nature to control chronic inflammation in obesity and cancer

A Kariagina, AI Doseff - International Journal of Molecular Sciences, 2022 - mdpi.com
Flavones are natural phytochemicals broadly distributed in our diet. Their anti-inflammatory
properties provide unique opportunities to control the innate immune system and …

miR-21-3p controls sepsis-associated cardiac dysfunction via regulating SORBS2

H Wang, Y Bei, S Shen, P Huang, J Shi, J Zhang… - Journal of molecular and …, 2016 - Elsevier
Cardiac dysfunction with sepsis is a major cause of death in intensive care units. Several
lines of evidence have revealed the potential of microRNAs (miRNAs, miRs) as biomarkers …

Phenolic compounds exerting lipid-regulatory, anti-inflammatory and epigenetic effects as complementary treatments in cardiovascular diseases

L Toma, GM Sanda, LS Niculescu, M Deleanu… - Biomolecules, 2020 - mdpi.com
Atherosclerosis is the main process behind cardiovascular diseases (CVD), maladies which
continue to be responsible for up to 70% of death worldwide. Despite the ongoing …