Molecular probes, chemosensors, and nanosensors for optical detection of biorelevant molecules and ions in aqueous media and biofluids
Synthetic molecular probes, chemosensors, and nanosensors used in combination with
innovative assay protocols hold great potential for the development of robust, low-cost, and …
innovative assay protocols hold great potential for the development of robust, low-cost, and …
Further dimensions for sensing in biofluids: distinguishing bioorganic analytes by the salt-induced adaptation of a cucurbit [7] uril-based chemosensor
Insufficient binding selectivity of chemosensors often renders biorelevant metabolites
indistinguishable by the widely used indicator displacement assay. Array-based …
indistinguishable by the widely used indicator displacement assay. Array-based …
Chemiluminescent Cucurbit[n]uril-Based Chemosensor for the Detection of Drugs in Biofluids
Chemiluminescence-based detection methods offer a superior signal-to-noise ratio and are
commonly adopted for biosensors. This work presents the design and implementation of a …
commonly adopted for biosensors. This work presents the design and implementation of a …
Electrochemical Detection of Drugs via a Supramolecular Cucurbit [7] uril-Based Indicator Displacement Assay
Electrochemical detection methods are attractive for developing miniaturized, disposable,
and portable sensors for molecular diagnostics. In this article, we present a cucurbit [7] uril …
and portable sensors for molecular diagnostics. In this article, we present a cucurbit [7] uril …
Cucurbit[n]uril-Immobilized Sensor Arrays for Indicator-Displacement Assays of Small Bioactive Metabolites
C Zhong, C Hu, R Kumar, V Trouillet… - ACS Applied Nano …, 2021 - ACS Publications
The patterned immobilization of chemosensors into nano/microarrays has often boosted
utilization in diagnostics and environmental sensing applications. While this is a standard …
utilization in diagnostics and environmental sensing applications. While this is a standard …
[HTML][HTML] Analyte sensing with unselectively binding synthetic receptors: virtues of time-resolved supramolecular assays
The cross-reactivity to many analytes is one major limitation of most synthetic receptors
(SRs) known so far. Herein, we show that through time-resolved competitive binding assays …
(SRs) known so far. Herein, we show that through time-resolved competitive binding assays …
Cucurbituril-mediated AIE: An unconventional indicator displacement assay for ketamine detection
K Yan, L Wang, H Zhou, Z Hua, P Xu, H Xu, Y Wang… - Dyes and …, 2022 - Elsevier
Typical AIE luminogens with extensive π-electron conjugation are limited in use on account
of their complex synthesis, high cost and environmental concerns. To this end, we report …
of their complex synthesis, high cost and environmental concerns. To this end, we report …
[HTML][HTML] Elucidating dissociation activation energies in host–guest assemblies featuring fast exchange dynamics
The ability to mediate the kinetic properties and dissociation activation energies (Ea) of
bound guests by controlling the characteristics of “supramolecular lids” in host–guest …
bound guests by controlling the characteristics of “supramolecular lids” in host–guest …
From Molecules to Materials: Collaborative Research at the Chemistry—Materials Science Interface and Lessons Learned in Cyclophane Chemistry
Z Hassan, E Zysman‐Colman… - Advanced Functional …, 2024 - Wiley Online Library
In the spirit of pursuing collaborative research at the interface of chemistry and materials
science for engineering cyclophane‐based functional systems, the journey from molecules …
science for engineering cyclophane‐based functional systems, the journey from molecules …
Polymersome-Encapsulated Chemosensors: New Design Strategies toward Biofluid-Applicable Cucurbit [7] uril Indicator Displacement Assays
The development of supramolecular cucurbit [7] uril-based chemosensors for the detection
of bioanalytes in biofluids such as untreated human serum and inside cells is a challenging …
of bioanalytes in biofluids such as untreated human serum and inside cells is a challenging …