Mycobacterium tuberculosis is a difficult pathogen to combat and the first-line drugs currently
in use are 40–60 years old. The need for new TB drugs is urgent, but the time to identify …

Mycobacterium tuberculosis causes more deaths in humans than any other bacterial
pathogen. The most recent data from the World Health Organization reveal that over 9 …

The increased prevalence of obesity among adolescent are associated with short and long
term morbidity and mortality outcomes raises major public health concern. The evidence …

The development of a macrophage-based, antitubercular high-throughput screening system
could expedite discovery programs for identifying novel inhibitors. In this study, the kinetics …

Mycobacterium tuberculosis (MTB) is a specific aerobic bacterium, but can survive under
hypoxic conditions, such as those in lung cheese necrosis, granulomas, or macrophages. It …

An ATP-based biocide susceptibility assay for mycobacteria was developed by optimizing
the cell lysis and assay conditions. Compared to the conventional agar plating method, the …

Despite progress in modern chemotherapy to combat tuberculosis, the causative pathogen
Mycobacterium tuberculosis (M. tb.) is far from eradicated. Bacillary resistance to anti …

Introduction: Mycobacterium tuberculosis kills more people than any other bacterial
pathogen. New drugs are required to shorten the treatment time and provide a viable …

Tuberculosis (TB) is among the top ten killer diseases and remains the number one cause of
death due to infection. A major bottleneck in TB research remains the availability of suitable …

O universo multicultural das escolas portuguesas e os indicadores de (in) sucesso escolar
dos descendentes de imigrantes tem conduzido à implementação de medidas em contexto …