Exosomes regulate neurogenesis and circuit assembly

P Sharma, P Mesci, C Carromeu… - Proceedings of the …, 2019 - National Acad Sciences
Exosomes are thought to be released by all cells in the body and to be involved in
intercellular communication. We tested whether neural exosomes can regulate the …

The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells

D Choi, L Montermini, DK Kim, B Meehan… - Molecular & Cellular …, 2018 - ASBMB
Glioblastoma multiforme (GBM) is a highly aggressive and heterogeneous form of primary
brain tumors, driven by a complex repertoire of oncogenic alterations, including the …

Promising RNA-based cancer gene therapy using extracellular vesicles for drug delivery

VW Xue, SCC Wong, G Song… - Expert Opinion on …, 2020 - Taylor & Francis
Introduction RNA-based cancer gene therapy shows potential in cancer treatment. However,
the safe and efficient transfer of therapeutic RNA to target cells has always been a …

Recent advances in the detection of glioblastoma, from imaging-based methods to proteomics and biosensors: A narrative review

A Hosseini, H Ashraf, F Rahimi, I Alipourfard… - Cancer Cell …, 2023 - Springer
Glioblastoma (GBM) is an aggressive type of cancer that originates in the cells called
astrocytes, which support the functioning of nerve cells. It can develop in either the brain or …

Identification of blood biomarkers in glioblastoma by SWATH mass spectrometry and quantitative targeted absolute proteomics

E Miyauchi, T Furuta, S Ohtsuki, M Tachikawa… - PloS one, 2018 - journals.plos.org
Molecular biomarkers in blood are needed to aid the early diagnosis and clinical
assessment of glioblastoma (GBM). Here, in order to identify biomarker candidates in …

Physical characterization and profiling of airway epithelial derived exosomes using light scattering

M Kesimer, R Gupta - Methods, 2015 - Elsevier
Exosomes and other extracellular vesicles have been gaining interest during the last
decade due to their emerging role in biology and, disease pathogenesis and their biomarker …

Plasma-derived extracellular vesicles reveal galectin-3 binding protein as potential biomarker for early detection of glioma

R Rana, K Chauhan, P Gautam, M Kulkarni… - Frontiers in …, 2021 - frontiersin.org
Gliomas are the most common type of the malignant brain tumor, which arise from glial cells.
They make up about 40% of all primary brain tumors and around 70% of all primary …

Machine‐learning based radiogenomics analysis of MRI features and metagenes in glioblastoma multiforme patients with different survival time

X Liao, B Cai, B Tian, Y Luo, W Song… - Journal of cellular and …, 2019 - Wiley Online Library
Background This study aimed to examine multi‐dimensional MRI features' predictability on
survival outcome and associations with differentially expressed Genes (RNA Sequencing) in …

Altered transcriptional regulatory proteins in glioblastoma and YBX1 as a potential regulator of tumor invasion

MK Gupta, RV Polisetty, R Sharma, RA Ganesh… - Scientific reports, 2019 - nature.com
We have studied differentially regulated nuclear proteome of the clinical tissue specimens of
glioblastoma (GBM, WHO Grade IV) and lower grades of gliomas (Grade II and III) using …

The big picture of glioblastoma malignancy: A meta-analysis of glioblastoma proteomics to identify altered biological pathways

AKW Tribe, MJ McConnell, PH Teesdale-Spittle - ACS omega, 2021 - ACS Publications
Glioblastoma is a highly malignant cancer with no effective treatment. It is vital to elucidate
the mechanisms which drive glioblastoma in order to identify therapeutic targets. The …