Cellular Effects of Pyocyanin, a Secreted Virulence Factor of Pseudomonas aeruginosa

S Hall, C McDermott, S Anoopkumar-Dukie… - Toxins, 2016 - mdpi.com
Pyocyanin has recently emerged as an important virulence factor produced by
Pseudomonas aeruginosa. The redox-active tricyclic zwitterion has been shown to have a …

Pyocyanin effects on respiratory epithelium: relevance in Pseudomonas aeruginosa airway infections

B Rada, TL Leto - Trends in microbiology, 2013 - cell.com
Pseudomonas aeruginosa (PA) uses several virulence factors to establish chronic
respiratory infections in bronchiectasis, chronic obstructive pulmonary disease, and cystic …

[HTML][HTML] Role of quorum sensing in bacterial infections

I Castillo-Juárez, T Maeda… - World Journal of …, 2015 - ncbi.nlm.nih.gov
Quorum sensing (QS) is cell communication that is widely used by bacterial pathogens to
coordinate the expression of several collective traits, including the production of multiple …

Aiding nature's organelles: artificial peroxisomes play their role

P Tanner, V Balasubramanian, CG Palivan - Nano letters, 2013 - ACS Publications
A major goal in medical research is to develop artificial organelles that can implant in cells to
treat pathological conditions or to support the design of artificial cells. Several attempts have …

Fucoidan-Stabilized Gold Nanoparticle-Mediated Biofilm Inhibition, Attenuation of Virulence and Motility Properties in Pseudomonas aeruginosa PAO1

F Khan, P Manivasagan, JW Lee, DTN Pham, J Oh… - Marine drugs, 2019 - mdpi.com
The emergence of antibiotic resistance in Pseudomonas aeruginosa due to biofilm formation
has transformed this opportunistic pathogen into a life-threatening one. Biosynthesized …

Unraveling Pseudomonas aeruginosa and Candida albicans Communication in Coinfection Scenarios: Insights Through Network Analysis

T Grainha, P Jorge, D Alves, SP Lopes… - Frontiers in Cellular …, 2020 - frontiersin.org
Modern medicine is currently facing huge setbacks concerning infection therapeutics as
microorganisms are consistently knocking down every antimicrobial wall set before them …

Candida albicans and Pseudomonas aeruginosa Interaction, with Focus on the Role of Eicosanoids

R Fourie, R Ells, CW Swart, OM Sebolai… - Frontiers in …, 2016 - frontiersin.org
Candida albicans is commonly found in mixed infections with Pseudomonas aeruginosa,
especially in the lungs of cystic fibrosis (CF) patients. Both of these opportunistic pathogens …

Beyond Antagonism: The Interaction Between Candida Species and Pseudomonas aeruginosa

R Fourie, CH Pohl - Journal of Fungi, 2019 - mdpi.com
There are many examples of the interaction between prokaryotes and eukaryotes. One such
example is the polymicrobial colonization/infection by the various opportunistic pathogenic …

Culture-free diagnostics of Pseudomonas aeruginosa infection by silver nanorod array based SERS from clinical sputum samples

X Wu, J Chen, X Li, Y Zhao, SM Zughaier - … : Nanotechnology, Biology and …, 2014 - Elsevier
Pseudomonas aeruginosa can cause major infection in immunocompromised patients, and
successful antibiotic treatment of the infection relies on accurate and rapid identification of …

Pseudomonas aeruginosa Pyocyanin Activates NRF2-ARE-Mediated Transcriptional Response via the ROS-EGFR-PI3K-AKT/MEK-ERK MAP Kinase Signaling in …

Y Xu, C Duan, Z Kuang, Y Hao, JL Jeffries, GW Lau - PLoS One, 2013 - journals.plos.org
The redox-active pyocyanin (PCN) secreted by the respiratory pathogen Pseudomonas
aeruginosa generates reactive oxygen species (ROS) and causes oxidative stress to …