Factor XIII and fibrinogen are unusual among clotting factors in that neither is a serine
protease. Fibrin is the main protein constituent of the blood clot, which is stabilized by factor …

Intracerebral haemorrhage (ICH) is associated with the greatest morbidity and mortality of all
stroke subtypes. Established risk factors for ICH include hypertension, alcohol use, current …

BACKGROUND: Although warfarin and other anticoagulants can prevent ischemic events,
they can cause hemorrhage. Quantifying the rate of hemorrhage is crucial for determining …

Completely updated edition, written by a close-knit author team Presents a unique approach
to stroke-integrated clinical management that weaves together causation, presentation …

Background and Purpose—The functional integrity of the hemostatic system is a prerequisite
for the safe performance of neurosurgical procedures. To monitor the individual coagulation …

Arterial and venous thromboses, with their clinical manifestations such as stroke, myocardial
infarction (MI), or pulmonary embolism, are the major causes of death in developed …

Summary Factor V Leiden (FVL) and ABO (H) blood groups are the common influences on
haemostasis and retrospective studies have linked FVL with pregnancy complications …

Thrombosis results from the interaction between predisposing genetic polymorphisms and
acquired risk factors. Two of the main prothrombotic alleles, Factor V (FV) Leiden and …

Background: Endothelial cell protein C receptor (EPCR) binds protein C through its γ‐
carboxyglutamic acid (Gla) domain and enhances its thrombin–thrombomodulin complex …

Results from epidemological studies are consistent with the hypothesis that disparities in
venous thromboembolism (VTE) burden are attributable to differences in genetic structure …