Plant-associated endophytes define an important symbiotic association in nature and are
established bio-reservoirs of plant-derived natural products. Endophytes colonize the …

Endophytic fungi or endophytes exist widely inside the healthy tissues of living plants, and
are important components of plant micro-ecosystems. Over the long period of evolution …

Endophytic fungi comprise host-associated fungal communities which thrive within the
tissues of host plants and produce a diverse range of secondary metabolites with various …

Biotechnology is playing a vital alternative role in the production of pharmaceutical plant
secondary metabolites to support industrial production and mitigate over-exploitation of …

The escalating demand for secondary metabolites in international markets poses a severe
threat to many plant species. An unscrupulous collection is also the immediate challenge to …

Fungal endophytes are well-established sources of biologically active natural compounds
with many producing pharmacologically valuable specific plant-derived products. This …

Cancer is a major cause of death worldwide, with an increasing number of cases being
reported annually. The elevated rate of mortality necessitates a global challenge to explore …

The seminal discovery of paclitaxel from endophytic fungus Taxomyces andreanae was a
milestone in recognizing the immense potential of endophytic fungi as prolific producers of …

Covering: 1990 to 2010 This is a review of anticancer agents isolated from endophytic fungi
from 1990–2010. Endophytic fungi are defined as fungi that live asymptomatically within the …

DNA topoisomerases I and II (Top1 and Top2) are established molecular targets of
anticancer drugs. 1-5 Mammalian somatic cells express six topoisomerase genes: two TOP1 …