The devastating clinical consequences of child abuse and neglect: increased disease vulnerability and poor treatment response in mood disorders

ETC Lippard, CB Nemeroff - American journal of psychiatry, 2023 - psychiatryonline.org
A large body of evidence has demonstrated that exposure to childhood maltreatment at any
stage of development can have long-lasting consequences. It is associated with a marked …

[HTML][HTML] Cortisol and development of depression in adolescence and young adulthood–a systematic review and meta-analysis

Z Zajkowska, N Gullett, A Walsh, V Zonca… - …, 2022 - Elsevier
Introduction Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis has been
implicated in the development of major depressive disorder (MDD) in adulthood. Less work …

Cross-disorder analysis of brain structural abnormalities in six major psychiatric disorders: a secondary analysis of mega-and meta-analytical findings from the …

N Opel, J Goltermann, M Hermesdorf, K Berger… - Biological …, 2020 - Elsevier
Background Neuroimaging studies have consistently reported similar brain structural
abnormalities across different psychiatric disorders. Yet, the extent and regional distribution …

ENIGMA MDD: seven years of global neuroimaging studies of major depression through worldwide data sharing

L Schmaal, E Pozzi, T C. Ho, LS Van Velzen… - Translational …, 2020 - nature.com
A key objective in the field of translational psychiatry over the past few decades has been to
identify the brain correlates of major depressive disorder (MDD). Identifying measurable …

The brain structure, immunometabolic and genetic mechanisms underlying the association between lifestyle and depression

Y Zhao, L Yang, BJ Sahakian, C Langley… - Nature Mental …, 2023 - nature.com
Lifestyle factors have been acknowledged to be modifiable targets that can be used to
counter the increasing prevalence of depression. This study aims to investigate combining …

Critical appraisal of major depression with suicidal ideation

M Pompili - Annals of general psychiatry, 2019 - Springer
Background Regardless of its nature, suicidal ideation, in the absence of another diagnosis,
is quintessentially associated with major clinical depression. Although for the characteristics …

Altered brain dynamic in major depressive disorder: state and trait features

N Javaheripour, L Colic, N Opel, M Li… - Translational …, 2023 - nature.com
Temporal neural synchrony disruption can be linked to a variety of symptoms of major
depressive disorder (MDD), including mood rigidity and the inability to break the cycle of …

[HTML][HTML] A systematic review of the association between biological markers and environmental stress risk factors for adolescent depression

Z Zajkowska, A Walsh, V Zonca, N Gullett… - Journal of psychiatric …, 2021 - Elsevier
Introduction Although the aetiology and pathophysiology of depression are multifactorial, to
date most studies have examined either biological or environmental mechanisms without …

Temporal stability and state-dependence of retrospective self-reports of childhood maltreatment in healthy and depressed adults.

J Goltermann, S Meinert, C Hülsmann… - Psychological …, 2023 - psycnet.apa.org
Retrospective self-reports of childhood maltreatment (CM) are widely used. However, their
validity has been questioned due to potential depressive bias. Yet, investigations of this …

The mediating effect of self-compassion on the relationship between childhood maltreatment and depression

J Tao, K He, J Xu - Journal of affective disorders, 2021 - Elsevier
Background Depression is the leading cause of suicide. Childhood maltreatment is an
important influencing factor for depression in adulthood. However, the mediating effect of …