This paper briefly reviews the physiological components of the microcirculation, focusing on
its function in homeostasis and its central function in the realization of oxygen transport to …

The transport of suspensions of microparticles in confined environments is associated with
complex phenomena at the interface of fluid mechanics and soft matter. Indeed, the …

Classically, mitochondria have largely been believed to influence the development of illness
by modulating cell metabolism and determining the rate of production of high-energy …

Immediate and early trauma deaths are determined by primary brain injuries, or significant
blood loss (haemorrhagic shock), while late mortality is caused by secondary brain injuries …

Regional tissue distress caused by microcirculatory dysfunction and mitochondrial
depression underlies the condition in sepsis and shock where, despite correction of …

Beyond haemostasis, platelets have emerged as versatile effectors of the immune response.
The contribution of platelets in inflammation, tissue integrity and defence against infections …

Sepsis is a systemic response to infection, and symptoms are produced by host defense
systems rather than by the invading pathogens. Amongst the most prominent features of …

As a cornerstone of the innate immune response, neutrophils are the archetypical
phagocytic cell; they actively seek out, ingest, and destroy pathogenic microorganisms. To …

STUDY OBJECTIVE: To study early microcirculatory perfusion indices in patients with
severe sepsis/septic shock, compare early microcirculatory indices in sepsis survivors …

Red blood cells can be stored in liquid suspension in approved additive solutions for
periods up to 6weeks with 0.4% hemolysis, 84% 24-h in vivo recovery, and normal …