Natural product derived phytochemicals in managing acute lung injury by multiple mechanisms

YQ He, CC Zhou, LY Yu, L Wang, J Deng… - Pharmacological …, 2021 - Elsevier
Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome
(ARDS) as common life-threatening lung diseases with high mortality rates are mostly …

Antiviral and immunomodulatory activity of curcumin: A case for prophylactic therapy for COVID-19

RK Thimmulappa, KK Mudnakudu-Nagaraju… - Heliyon, 2021 - cell.com
Abstract Coronavirus disease-19 (COVID-19), a devastating respiratory illness caused by
SARS-associated coronavirus-2 (SARS-CoV-2), has already affected over 64 million people …

Intravenous vitamin C for reduction of cytokines storm in acute respiratory distress syndrome

A Boretti, BK Banik - PharmaNutrition, 2020 - Elsevier
The recent outbreak of Covid19 has required urgent treatments for numerous patients. No
suitable vaccines or antivirals are available for Covid19. The efficiency against Covid19 of …

Curcumin, a traditional spice component, can hold the promise against COVID-19?

VK Soni, A Mehta, YK Ratre, AK Tiwari, A Amit… - European Journal of …, 2020 - Elsevier
The severity of the recent pandemic and the absence of any specific medication impelled the
identification of existing drugs with potential in the treatment of Coronavirus disease-2019 …

Controlling cytokine storm is vital in COVID-19

L Tang, Z Yin, Y Hu, H Mei - Frontiers in immunology, 2020 - frontiersin.org
Corona virus disease 2019 (COVID-19) has caused a global outbreak and severely posed
threat to people's health and social stability. Mounting evidence suggests that …

The inhibitory effect of curcumin on virus-induced cytokine storm and its potential use in the associated severe pneumonia

Z Liu, Y Ying - Frontiers in cell and developmental biology, 2020 - frontiersin.org
Coronavirus infection, including SARS-CoV, MERS-CoV, and SARS-CoV2, causes daunting
diseases that can be fatal because of lung failure and systemic cytokine storm. The …

Antiinflammatory potential of nano‐curcumin as an alternative therapeutic agent for the treatment of mild‐to‐moderate hospitalized COVID‐19 patients in a placebo …

A Asadirad, R Nashibi, A Khodadadi… - Phytotherapy …, 2022 - Wiley Online Library
The present study conducted a placebo‐controlled clinical trial to evaluate the impact of
nano‐curcumin on the inflammatory cytokines in mild‐to‐moderate hospitalized COVID‐19 …

Nanocurcumin potently inhibits SARS-CoV-2 spike protein-induced cytokine storm by deactivation of MAPK/NF-κB signaling in epithelial cells

VK Sharma, Prateeksha, SP Singh… - ACS Applied Bio …, 2022 - ACS Publications
Interleukin-mediated deep cytokine storm, an aggressive inflammatory response to SARS-
CoV-2 virus infection in COVID-19 patients, is correlated directly with lung injury, multi-organ …

EGYVIR: An immunomodulatory herbal extract with potent antiviral activity against SARS-CoV-2

WH Roshdy, HA Rashed, A Kandeil, A Mostafa… - PLoS …, 2020 - journals.plos.org
Due to the challenges for developing vaccines in devastating pandemic situations of severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), developing and screening of …

COVID‐19: A case for inhibiting NLRP3 inflammasome, suppression of inflammation with Curcumin?

A Saeedi‐Boroujeni… - Basic & Clinical …, 2021 - Wiley Online Library
Curcumin is the effective ingredient of turmeric, sometimes used as a painkiller in traditional
medicine. It has extensive biological properties such as anti‐inflammatory and antioxidant …