Together with core histones, which make up the nucleosome, the linker histone (H1) is one
of the five main histone protein families present in chromatin in eukaryotic cells. H1 binds to …

Post-translational modification (PTM) in histone proteins is a covalent modification which
mainly consists of methylation, phosphorylation, acetylation, ubiquitylation, SUMOylation …

To enhance therapeutic efficacy and reduce adverse effects, practitioners of traditional
Chinese medicine (TCM) prescribe a combination of plant species/minerals, called …

The lysine-rich H1 histone family in mammals includes eleven different subtypes, and thus it
is the most divergent class of histone proteins. The central globular H1 domain …

Histone H1 is the most variable histone and its role at the epigenetic level is less
characterized than that of core histones. In vertebrates, H1 is a multigene family, which can …

Background Linker histone H1 is a structural component of chromatin. It exists as a family of
related proteins known as variants and/or subtypes. H1. 1, H1. 2, H1. 3, H1. 4 and H1. 5 are …

At least six histone H1 variants exist in somatic mammalian cells that bind to the linker DNA
and stabilize the nucleosome particle contributing to higher order chromatin compaction. In …

The linker histone H1 is involved in maintaining higher-order chromatin structures and
displays dynamic nuclear mobility, which may be regulated by posttranslational …

H1 histones, isolated from logarithmically growing and mitotically enriched human
lymphoblastic T-cells (CCRF-CEM), were fractionated by reversed phase and hydrophilic …

Histone H1 isoforms isolated from asynchronously grown HeLa cells were subjected to
enzymatic digestion and analyzed by nano-flow reversed-phase high performance liquid …