Bioinspired polymer vesicles and membranes for biological and medical applications

CG Palivan, R Goers, A Najer, X Zhang, A Car… - Chemical society …, 2016 - pubs.rsc.org
Biological membranes play an essential role in living organisms by providing stable and
functional compartments, preserving cell architecture, whilst supporting signalling and …

Emerging era of “somes”: Polymersomes as versatile drug delivery carrier for cancer diagnostics and therapy

AK Sharma, P Prasher, AA Aljabali, V Mishra… - Drug delivery and …, 2020 - Springer
Over the past two decades, polymersomes have been widely investigated for the delivery of
diagnostic and therapeutic agents in cancer therapy. Polymersomes are stable polymeric …

Review of contemporary self-assembled systems for the controlled delivery of therapeutics in medicine

LL Osorno, AN Brandley, DE Maldonado, A Yiantsos… - Nanomaterials, 2021 - mdpi.com
The novel and unique design of self-assembled micro and nanostructures can be tailored
and controlled through the deep understanding of the self-assembly behavior of amphiphilic …

Axial pharmaceutical properties of liposome in cancer therapy: Recent advances and perspectives

SH Kiaie, S Mojarad-Jabali, F Khaleseh… - International journal of …, 2020 - Elsevier
Abstract Evaluation of axial properties including preparation, surface functionalization, and
pharmacokinetics for delivery of pharmacologically active molecules and genes lead to …

LRP1-mediated pH-sensitive polymersomes facilitate combination therapy of glioblastoma in vitro and in vivo

C He, Z Zhang, Y Ding, K Xue, X Wang, R Yang… - Journal of …, 2021 - Springer
Background Glioblastoma (GBM) is the most invasive primary intracranial tumor, and its
effective treatment is one of the most daunting challenges in oncology. The blood–brain …

Acid-disintegratable polymersomes of pH-responsive amphiphilic diblock copolymers for intracellular drug delivery

L Wang, G Liu, X Wang, J Hu, G Zhang, S Liu - Macromolecules, 2015 - ACS Publications
Supramolecular vesicles, also referred to as polymersomes, self-assembled from
amphiphilic polymers capable of synchronically loading with both hydrophilic and …

Advances in targeted drug delivery approaches for the central nervous system tumors: the inspiration of nanobiotechnology

J Meng, V Agrahari, I Youm - Journal of Neuroimmune Pharmacology, 2017 - Springer
At present, brain tumor is among the most challenging diseases to treat and the therapy is
limited by the lack of effective methods to deliver anticancer agents across the blood-brain …

Nanoparticle-based co-delivery of siRNA and paclitaxel for dual-targeting of glioblastoma

J Yang, Q Zhang, Y Liu, X Zhang, W Shan, S Ye… - …, 2020 - Taylor & Francis
Aim: To explore the therapeutic effect of nanoparticle-based dual-targeting delivery of
antitumor agents for glioblastoma treatment. Materials & methods: A hepatitis B core protein …

Preclinical evaluation of binimetinib (MEK162) delivered via polymeric nanocarriers in combination with radiation and temozolomide in glioma

F Bikhezar, RM de Kruijff, AJGM van der Meer… - Journal of Neuro …, 2020 - Springer
Background and purpose Glioblastoma multiforme (GBM) is the most aggressive subtype of
malignant gliomas, with an average survival rate of 15 months after diagnosis. More than …

Latest development and versatile applications of highly integrating drug delivery patch

Y Chen, Q An, K Teng, Y Zhang, Y Zhao - European Polymer Journal, 2022 - Elsevier
Drug administration is an indispensable part of human life and human society. Delivery
patch provides a comfortable and convenient manner to treat various diseases with minimal …