Significance: The global burden of diabetic wounds, particularly diabetic foot ulcers,
continues to have large economic and social impact throughout the world. Current strategies …

Over the past two decades, mesenchymal stem cells (MSCs) have shown promising
therapeutic effects both in preclinical studies (in animal models of a wide range of diseases) …

Traumatic spinal cord injury (SCI) is a leading cause of permanent neurologic disabilities in
young adults. Functional impairments after SCI are substantially attributed to the progressive …

Animal model studies and first clinical trials have demonstrated the safety and efficacy of the
mesenchymal stem cells'(MSCs) transplantation in stroke. Intra-arterial (IA) administration …

Systemic transplantation of mesenchymal stem cells (MSCs) is a promising approach for the
treatment of ischemia-associated disorders, including stroke. However, exact mechanisms …

Over the past decade, cell therapy has found many applications in the treatment of different
diseases. Some of the cells already used in clinical practice include stem cells and CAR-T …

Transplantation of various types of stem cells as a possible therapy for stroke has been
tested for years, and the results are promising. Recent investigations have shown that the …

Background Cell therapy using neural progenitor cells (NPCs) is a promising approach for
ischemic stroke treatment according to the results of multiple preclinical studies in animal …

Stem cell therapy for ischemic stroke holds great promise for the treatment of neurological
impairment and has moved from the laboratory into early clinical trials. The mechanism of …

Although cell therapy has been applied in regenerative medicine for decades, recent years
have seen greatly increased attention being given to the use of stem cell-based derivatives …