Quantitatives studies on the mammalian cerebellum

RJ Harvey, RMA Napper - Progress in neurobiology, 1991 - Elsevier
QUANTITATIVE STUDIES ON THE MAMMALIAN CEREBELLUM Page 1 Progress in
Neurobiology Vol. 36, pp. 437 to 463, 1991 0301-0082/91/$0.00 + 0.50 Printed in Great Britain …

Patterned Purkinje cell death in the cerebellum

JR Sarna, R Hawkes - Progress in neurobiology, 2003 - Elsevier
The object of this review is to assemble much of the literature concerning Purkinje cell death
in cerebellar pathology and to relate this to what is now known about the complex …

Disproportionate atrophy of cerebral white matter in chronic alcoholics

SM de la Monte - Archives of neurology, 1988 - jamanetwork.com
• Morphometric analysis of postmortem brains from chronic ethyl alcohol abusers and
controls was performed to determine the regional distribution and extent of atrophy in the …

Are we drinking our neurones away?

C Harper, J Kril, J Daly - Br Med J (Clin Res Ed), 1987 - bmj.com
A quantitative neuropathological necropsy study of the human cerebral cortex showed that
the number of cortical neurones in the superior frontal cortex in chronic alcoholic patients is …

Cerebellar and frontal hypometabolism in alcoholic cerebellar degeneration studied with positron emission tomography

S Gilman, K Adams, RA Koeppe… - Annals of Neurology …, 1990 - Wiley Online Library
Local cerebral metabolic rate for glucose was studied utilizing 18F‐2‐fluoro‐2‐deoxy‐D‐
glucose and positron emission tomography (PET) in 14 chronically alcohol‐dependent …

Neuropathology of alcoholism

CG HARPER, JJ KRIL - Alcohol and alcoholism, 1990 - academic.oup.com
There are wide ranging effects of alcohol on the nervous system. Some interfere with
physiological and neurochemical functions but ultimately structural damage occurs. During …

Do alcoholics drink their neurons away?

GB Jensen, B Pakkenberg - The Lancet, 1993 - Elsevier
Although it is commonly believed that chronic alcohol abuse results in loss of neocortical
neurons, this assumption has not been properly tested. We used new stereological …

New insights on neurobiological mechanisms underlying alcohol addiction

C Cui, A Noronha, H Morikawa, VA Alvarez… - …, 2013 - Elsevier
Alcohol dependence/addiction is mediated by complex neural mechanisms that involve
multiple brain circuits and neuroadaptive changes in a variety of neurotransmitter and …

Mechanisms of ethanol-induced degeneration in the developing, mature, and aging cerebellum

P Jaatinen, J Rintala - The Cerebellum, 2008 - Springer
The adverse effects of acute and chronic ethanol exposure on cerebellar functions have
been acknowledged for decades, in terms of impaired control of movement and balance. In …

Don't get too excited: mechanisms of glutamate-mediated Purkinje cell death

JE Slemmer, CI De Zeeuw, JT Weber - Progress in brain research, 2005 - Elsevier
Purkinje cells (PCs) present a unique cellular profile in both the cerebellum and the brain.
Because they represent the only output cell of the cerebellar cortex, they play a vital role in …