Progress in the field of prosthetic cardiovascular devices has significantly contributed to the
rapid advancements in cardiac therapy during the last four decades. The concept of …

Despite decades of research related to hemolysis, the accuracy of prediction algorithms for
complex flows leaves much to be desired. Fundamental questions remain about how …

Ventricular assist devices (VADs) have already helped many patients with heart failure but
have the potential to assist more patients if current problems with blood damage (hemolysis …

To assist the development and application of blood‐contacting medical devices, two novel
flow‐through Couette‐type blood‐shearing devices have been developed to study the …

Purpose Device-induced blood damage contributes the hemolysis, thrombosis and bleeding
complications in patients supported with ventricular assist device (VAD). This study aims to …

Centrifugal blood pumps are usually designed with secondary flow paths to avoid flow dead
zones and reduce the risk of thrombosis. Due to the secondary flow path, the intensity of …

An extended pattern search approach is presented for the optimization of the placement of
wind turbines on a wind farm. Problem-specific extensions infuse stochastic characteristics …

With the increasing use of artificial organs, blood damage has been raising ever more
clinical concern. Blood trauma is in fact a major complication resulting from the implantation …

Protein degradation is a major concern for protein-based therapeutics. It may alter the
biological activity of the product and raise the potential for undesirable effects on the …

In this study, the flow features and device‐associated blood trauma in 4 clinical ventricular
assist devices (VADs; 2 implantable axial VADs, 1 implantable centrifugal VAD, and 1 …