20-HETE in the regulation of vascular and cardiac function
P Rocic, ML Schwartzman - Pharmacology & therapeutics, 2018 - Elsevier
HETE, the ω-hydroxylation product of arachidonic acid catalyzed by enzymes of the
cytochrome P450 (CYP) 4A and 4F gene families, is a bioactive lipid mediator with potent …
cytochrome P450 (CYP) 4A and 4F gene families, is a bioactive lipid mediator with potent …
Eicosanoid blood vessel regulation in physiological and pathological states
JD Imig - Clinical Science, 2020 - portlandpress.com
Arachidonic acid can be metabolized in blood vessels by three primary enzymatic pathways;
cyclooxygenase (COX), lipoxygenase (LO), and cytochrome P450 (CYP). These eicosanoid …
cyclooxygenase (COX), lipoxygenase (LO), and cytochrome P450 (CYP). These eicosanoid …
[HTML][HTML] Thick ascending limb sodium transport in the pathogenesis of hypertension
A Gonzalez-Vicente, F Saez… - Physiological …, 2018 - journals.physiology.org
The thick ascending limb plays a key role in maintaining water and electrolyte balance. The
importance of this segment in regulating blood pressure is evidenced by the effect of loop …
importance of this segment in regulating blood pressure is evidenced by the effect of loop …
Vascular endothelial overexpression of human CYP2J2 (Tie2-CYP2J2 Tr) modulates cardiac oxylipin profiles and enhances coronary reactive hyperemia in mice
Arachidonic acid is metabolized to epoxyeicosatrienoic acids (EETs) by cytochrome (CYP)
P450 epoxygenases, and to ω-terminal hydroxyeicosatetraenoic acids (HETEs) by ω …
P450 epoxygenases, and to ω-terminal hydroxyeicosatetraenoic acids (HETEs) by ω …
Vascular endothelial over-expression of human soluble epoxide hydrolase (Tie2-sEH Tr) attenuates coronary reactive hyperemia in mice: Role of oxylipins and ω …
Cytochromes P450 metabolize arachidonic acid (AA) into two vasoactive oxylipins with
opposing biologic effects: epoxyeicosatrienoic acids (EETs) and omega-(ω)-terminal …
opposing biologic effects: epoxyeicosatrienoic acids (EETs) and omega-(ω)-terminal …
[HTML][HTML] Endothelin receptor A and p66Shc regulate spontaneous Ca2+ oscillations in smooth muscle cells controlling renal arterial spontaneous motion
Adaptor protein p66Shc is overexpressed in smooth muscle cells of renal resistance vessels
of hypertensive salt-sensitive rats and is involved in the regulation of renal vascular tone. We …
of hypertensive salt-sensitive rats and is involved in the regulation of renal vascular tone. We …
Reduced coronary reactive hyperemia in mice was reversed by the soluble epoxide hydrolase inhibitor (t-AUCB): Role of adenosine A2A receptor and plasma …
Coronary reactive hyperemia (CRH) protects the heart against ischemia. Adenosine A 2A
AR–deficient (A 2A AR−/−) mice have increased expression of soluble epoxide hydrolase …
AR–deficient (A 2A AR−/−) mice have increased expression of soluble epoxide hydrolase …
Evaluation of Vascular Control Mechanisms Utilizing Video Microscopy of Isolated Resistance Arteries of Rats
KM Lukaszewicz, MJ Durand, JRC Priestley… - JoVE (Journal of …, 2017 - jove.com
This protocol describes the use of in vitro television microscopy to evaluate vascular function
in isolated cerebral resistance arteries (and other vessels), and describes techniques for …
in isolated cerebral resistance arteries (and other vessels), and describes techniques for …
[引用][C] Endothelin receptor A and p66Shc regulate spontaneous Ca 2 oscillations in smooth muscle cells controlling renal arterial spontaneous motion
O Palygin, BS Miller, Y Nishijima, DX Zhang…