Strains of bacteria resistant to antibiotics, particularly those that are multiresistant, are an
increasing major health care problem around the world. It is now abundantly clear that both …

Bacterial antimicrobial resistance (AMR) is constantly evolving and horizontal gene transfer
through plasmids plays a major role. The identification of plasmid characteristics and their …

Plasmids belonging to incompatibility groups A and C (now A/C) were among the earliest to
be associated with antibiotic resistance in Gram-negative bacteria. A/C plasmids are large …

Disinfection regimes are considered the most solid strategy to reduce microbial risks in
drinking water, but their roles in shaping the antibiotic resistome are poorly understood. This …

Plasmids of incompatibility group A/C (IncA/C) are becoming increasingly prevalent within
pathogenic Enterobacteriaceae. They are associated with the dissemination of multiple …

The large, broad host range IncC plasmids are important contributors to the spread of key
antibiotic resistance genes and over 200 complete sequences of IncC plasmids have been …

We recently showed that, in the absence of RecA-dependent homologous recombination,
the Tnp26 transposase catalyzes cointegrate formation via a conservative reaction between …

The bacterial enzyme New Delhi metallo-β-lactamase hydrolyzes almost all β-lactam
antibiotics, including carbapenems, which are drugs of last resort for severe bacterial …

Multidrug-resistant (MDR) Proteus, especially those strains producing extended-spectrum β-
lactamases (ESBL) and carbapenemases, represents a major public health concern. In the …

ABSTRACT A Salmonella enterica serovar Corvallis strain was isolated from a wild bird in
Germany. This strain carried the IncA/C2 pRH-1238 plasmid. Complete sequencing of the …