Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions

MD Roberts, JJ McCarthy… - Physiological …, 2023 - journals.physiology.org
Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

Blood flow restriction training in clinical musculoskeletal rehabilitation: a systematic review and meta-analysis

L Hughes, B Paton, B Rosenblatt, C Gissane… - British journal of sports …, 2017 - bjsm.bmj.com
Background and objective Low-load exercise training with blood flow restriction (BFR) can
increase muscle strength and may offer an effective clinical musculoskeletal (MSK) …

Maximizing muscle hypertrophy: a systematic review of advanced resistance training techniques and methods

M Krzysztofik, M Wilk, G Wojdała, A Gołaś - International journal of …, 2019 - mdpi.com
Background: Effective hypertrophy-oriented resistance training (RT) should comprise a
combination of mechanical tension and metabolic stress. Regarding training variables, the …

Magnitude of muscle strength and mass adaptations between high-load resistance training versus low-load resistance training associated with blood-flow restriction: a …

ME Lixandrão, C Ugrinowitsch, R Berton, FC Vechin… - Sports medicine, 2018 - Springer
Background Low-load resistance training (< 50% of one-repetition maximum [1RM])
associated with blood-flow restriction (BFR-RT) has been thought to promote increases in …

Comparing the effectiveness of blood flow restriction and traditional heavy load resistance training in the post-surgery rehabilitation of anterior cruciate ligament …

L Hughes, B Rosenblatt, F Haddad, C Gissane… - Sports Medicine, 2019 - Springer
Background We implemented a blood flow restriction resistance training (BFR-RT)
intervention during an 8-week rehabilitation programme in anterior cruciate ligament …

Skeletal muscle as an endocrine organ: PGC-1α, myokines and exercise

S Schnyder, C Handschin - Bone, 2015 - Elsevier
An active lifestyle is crucial to maintain health into old age; inversely, sedentariness has
been linked to an elevated risk for many chronic diseases. The discovery of myokines …

A review on the mechanisms of blood-flow restriction resistance training-induced muscle hypertrophy

SJ Pearson, SR Hussain - Sports medicine, 2015 - Springer
It has traditionally been believed that resistance training can only induce muscle growth
when the exercise intensity is greater than 65% of the 1-repetition maximum (RM). However …

Exercise with blood flow restriction: an updated evidence-based approach for enhanced muscular development

BR Scott, JP Loenneke, KM Slattery, BJ Dascombe - Sports medicine, 2015 - Springer
A growing body of evidence supports the use of moderate blood flow restriction (BFR)
combined with low-load resistance exercise to enhance hypertrophic and strength …

Potential mechanisms for a role of metabolic stress in hypertrophic adaptations to resistance training

BJ Schoenfeld - Sports medicine, 2013 - Springer
It is well established that regimented resistance training can promote increases in muscle
hypertrophy. The prevailing body of research indicates that mechanical stress is the primary …

Effect of blood‐flow restricted vs heavy‐load strength training on muscle strength: systematic review and meta‐analysis

BM Grønfeldt, J Lindberg Nielsen… - … journal of medicine …, 2020 - Wiley Online Library
Introduction Heavy‐load strength training (HLT) is generally considered the Gold Standard
exercise modality for inducing gains in skeletal muscle strength. However, use of heavy …