Molecular genetics of thrombotic myeloproliferative neoplasms: Implications in precision oncology

YC Chia, MJ Siti Asmaa, M Ramli, PY Woon, MF Johan… - Diagnostics, 2023 - mdpi.com
Classical BCR-ABL-negative myeloproliferative neoplasms (MPN) include polycythaemia
vera, essential thrombocythaemia, and primary myelofibrosis. Unlike monogenic disorders …

Implications of Janus kinase 2 mutation in embolic stroke of unknown source

G Trifan, N Shafi, FD Testai - Journal of Stroke and Cerebrovascular …, 2018 - Elsevier
The role of genetic mutations in cerebral ischemia is not completely understood. Among
these genetic variations, Philadelphia-negative gain-of-function mutation in the janus kinase …

Hematological relevance of JAK2 V617F and calreticulin mutations in Tunisian patients with essential thrombocythemia

M Abdelghani, H Hammami, W Zidi… - Journal of Clinical …, 2022 - Wiley Online Library
Background The genetic investigation of essential thrombocythemia (ET) has highlighted the
presence of driver mutations in ET. Janus kinase JAK2V617F and calreticulin (CALR) …

[PDF][PDF] Myeloproliferative Neoplasm Symptom Assessment Total Symptom Score (MPN-SAF TSS) in Chronic Myeloproliferative Neoplasms, Related with Genetic …

E Ümit, M Baysal, HO Kırkızlar… - Turkish Journal of …, 2024 - jag.journalagent.com
Abstract Myeloproliferative Neoplasm Symptom Assessment Total Symptom Score (MPN-
SAF TSS) is a surrogate marker for symptom evaluation in Chronic Myeloproliferative …

Correlation of Thrombosis and Clinicohematological Parameters with JAK2V617F Mutation in Philadelphia-Negative CMPNs: A Study from India

K Singh, V Pradeep, A Ahuja… - Journal of …, 2022 - thieme-connect.com
Objective Philadelphia-negative chronic myeloproliferative neoplasms (CMPNs), which
include polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis …

[PDF][PDF] Molecular genetics of thrombotic myeloproliferative neoplasms

YC Chia, S Asmaa, M Jusoh, M Ramli, PY Woon… - 2023 - pure-oai.bham.ac.uk
Classical BCR-ABL-negative myeloproliferative neoplasms (MPN) include polycythaemia
vera, essential thrombocythaemia, and primary myelofibrosis. Unlike monogenic disorders …

Myeloproliferative Neoplasms, an Acquired Thrombophilic State: JAK2 and Beyond

HP Pati, P Sharma - Indian Journal of Hematology and Blood Transfusion, 2016 - Springer
In the current issue of IJHBT, Uyanik et al.[1] present data from 101 patients with essential
thrombocythemia (ET) and polycythemia vera (PV) with reference to the development of …