Acid hydrazides, potent reagents for synthesis of oxygen-, nitrogen-, and/or sulfur-containing heterocyclic rings

P Majumdar, A Pati, M Patra, RK Behera… - Chemical …, 2014 - ACS Publications
Heterocycles form by far the largest of the classical divisions of organic chemistry. Moreover,
they are of immense importance not only both biologically and industrially but also to the …

Recent advances bioactive 1, 2, 4-triazole-3-thiones

ŞG Küçükgüzel, P Çıkla-Süzgün - European journal of medicinal chemistry, 2015 - Elsevier
Triazoles are heterocyclic compounds which have a five-membered ring of two carbon
atoms and three nitrogen atoms. These structures have been interest in the development of …

New pyrazole derivatives containing 1, 2, 4-triazoles and benzoxazoles as potent antimicrobial and analgesic agents

AM Vijesh, AM Isloor, P Shetty, S Sundershan… - European Journal of …, 2013 - Elsevier
Azole class of compounds are well known for their excellent therapeutic properties. Present
paper describes about the synthesis of three series of new 1, 2, 4-triazole and benzoxazole …

Synthesis and biological activity of Schiff and Mannich bases bearing 2, 4-dichloro-5-fluorophenyl moiety

MS Karthikeyan, DJ Prasad, B Poojary, KS Bhat… - Bioorganic & medicinal …, 2006 - Elsevier
A series of 2, 4-dichloro-5-fluorophenyl bearing Mannich base (4 and 5) was prepared from
triazole Schiff bases (3) by aminomethylation with formaldehyde and secondary/substituted …

Recent developments on 1, 2, 4-triazole nucleus in anticancer compounds: a review

R Kaur, A Ranjan Dwivedi, B Kumar… - Anti-Cancer Agents in …, 2016 - ingentaconnect.com
1, 2, 4-triazole is an important nucleus present in a large number of compounds. More than
thirty-five compounds containing this nucleus are introduced into the market. 1, 2, 4-triazole …

Heterocyclic scaffolds: centrality in anticancer drug development

I Ali, M Nadeem Lone, Z A. Al-Othman… - Current drug …, 2015 - benthamdirect.com
Cancer has been cursed for human beings for long time. Millions people lost their lives due
to cancer. Despite of the several anticancer drugs available, cancer cannot be cured; …

1, 2, 4-Triazoles: A review of synthetic approaches and the biological activity

S Maddila, R Pagadala… - Letters in Organic …, 2013 - benthamdirect.com
1, 2, 4-Triazoles and their derivatives have a distinct place in the field of medicinal and
pharmaceutical chemistry. These are used as lead compounds for the synthesis of …

Metal based biologically active compounds: Design, synthesis, and antibacterial/antifungal/cytotoxic properties of triazole-derived Schiff bases and their oxovanadium …

ZH Chohan, SH Sumrra, MH Youssoufi… - European journal of …, 2010 - Elsevier
A new series of oxovanadium (IV) complexes have been designed and synthesized with a
new class of triazole Schiff bases derived from the reaction of 3, 5-diamino-1, 2, 4-triazole …

Synthesis, determination of the lipophilicity, anticancer and antimicrobial properties of some fused 1, 2, 4-triazole derivatives

K Sztanke, T Tuzimski, J Rzymowska… - European journal of …, 2008 - Elsevier
3-Unsubstituted and 3-substituted-7-aryl-5H-6, 7-dihydroimidazo [2, 1-c][1, 2, 4] triazoles (1–
14) were designed and obtained from biologically active 1-aryl-2-hydrazonoimidazolidines …

Regioselective reaction: synthesis, characterization and pharmacological studies of some new Mannich bases derived from 1, 2, 4-triazoles

AM Isloor, B Kalluraya, P Shetty - European journal of medicinal chemistry, 2009 - Elsevier
In the present investigation, a series of new 4 [(3-substituted-1H-pyrazol-4-yl)
methyleneamino]-5-substituted-2-[(4-methylpiperzine-1-yl) methyl]-2H-1, 2, 4-triazole-3 (4H) …