Ovarian cancer (OC) grows and interacts constantly with a complex microenvironment, in
which immune cells, fibroblasts, blood vessels, signal molecules and the extracellular matrix …

In vitro models are necessary to study the pathophysiology of the disease and the
development of effective, tailored treatment methods owing to the complexity and …

Hydrogels represent a key element in the development of in vitro tumor models, by
mimicking the typical 3D tumor architecture in a physicochemical manner and allowing the …

Polysaccharide based hydrogels have been predominantly utilized as ink materials for 3D
bioprinting due to biocompatibility and cell responsive features. However, most hydrogels …

The development of non-invasive photothermal therapy (PTT) methods utilizing
nanoparticles as sensitizers is one of the most promising directions in modern oncology …

In this work, we analyzed the reliability of alginate-gelatin microcapsules as artificial tumor
model. These tumor-like scaffolds are characterized by their composition and stiffness (∼ 25 …

Breast cancer is the most common cancer among women, and even though treatments are
available, efficiency varies with the patients. In vitro 2D models are commonly used to …

Spheroids are in vitro three-dimensional multicellular microstructures able to mimic the
biological microenvironment, including the complexity of tumor architecture. Therefore …

The mechanical environment is important for tumorigenesis and progression. Tumor cells
can sense mechanical signals by mechanosensitive receptors, and these mechanical …

Photodynamic therapy (PDT) is a noninvasive therapeutic approach for the treatment of skin
cancer and diseases. 5-Aminolevulinic acid is a prodrug clinically approved for PDT. Once …