[0001] The invention relates to the use of RNA and an aqueous injection buffer containing a
sodium salt, a calcium salt, optionally a potassium salt and optionally also lactate, in the …

Plasmid-lipid particles which are useful for transfection of cells in vitro or in vivo are
described. The particles can be formed using either detergent dialysis methods or methods …

4,235,871. A 1 1/1980 Papahadjopoulos et al.... 424/19 therapeutic agent is encapsulated in
a lipid vesicle. Surface 4,394,448 A 7, 1983 Szoka, Jr. et al.............. 435,172 charges on the …

Correspondence Address: Mark K. Johnson(57) ABSTRACT Mirus Corporation 505 S. Rosa
Rd. The process comprises designing a polynucleotide, Such as Madison, WI 53719 (US) …

0004 Background Polymers are used for drug delivery for a variety of therapeutic purposes.
PolymerS have also been used in research for the delivery of nucleic acids (polynucleotides …

0001. The present invention relates to brushes primarily for use in brushing catheter lumina.
This application claims the benefit of priority to the United Kingdom application GB0402249 …

Novel lipid-nucleic acid particulate complexes which are useful for in vitro or in vivo gene
transfer are described. The particles can be formed using either detergent dialysis meth ods …

An polyampholyte is utilized in a condensed polynucleotide complex for purposes of nucleic
acid delivery to a cell. The complex can be formed with an appropriate amount of positive …

Plasmid-lipid particles which are useful for transfection of cells in vitro or in vivo are
described. The particles can be formed using either detergent dialysis methods or methods …

Described is a process for delivering an inhibitor directed against an expressible nucleic
acid Sequence in a mammal to inhibit RNA function. An RNA function inhibiting sequence …