SUMMARY A substantial amount of antisense transcription is a hallmark of gene expression
in eukaryotes. However, antisense transcription was first demonstrated in bacteria almost 50 …

The term 'transcriptional interference'(TI) is widely used but poorly defined in the literature.
There are a variety of methods by which one can interfere with the process or the product of …

Antimicrobial peptides are promising alternative antimicrobial agents. However, little is
known about whether resistance to small-molecule antibiotics leads to cross-resistance …

The small RNAs associated with the protein Hfq constitute one of the largest classes of post‐
transcriptional regulators known to date. Most previously investigated members of this class …

Elucidating the transcribed regions of the genome constitutes a fundamental aspect of
human biology, yet this remains an outstanding problem. To comprehensively identify …

Functional analysis of a genome requires accurate gene structure information and a
complete gene inventory. A dual experimental strategy was used to verify and correct the …

To study basic principles of transcriptome organization in bacteria, we analyzed one of the
smallest self-replicating organisms, Mycoplasma pneumoniae. We combined strand-specific …

Hfq, a bacterial member of the Sm family of RNA‐binding proteins, is required for the action
of many small regulatory RNAs that act by basepairing with target mRNAs. Hfq binds this …

Chemical synthesis is a well established route for producing many chemicals on a large
scale, but some drawbacks still exist in this process, such as unstable intermediates …

▪ Abstract Small noncoding RNAs have been found in all organisms, primarily as regulators
of translation and message stability. The most exhaustive searches have taken place in E …