Polyomavirus-associated nephropathy in renal transplantation: interdisciplinary analyses and recommendations

HH Hirsch, DC Brennan, CB Drachenberg… - …, 2005 - journals.lww.com
Polyomavirus-associated nephropathy (PVAN) is an emerging cause of kidney transplant
failure affecting 1–10% of patients. As uncertainty exists regarding risk factors, diagnosis …

Polyomavirus Bk

HH Hirsch, J Steiger - The Lancet infectious diseases, 2003 - thelancet.com
Polyomavirus hominis 1, better known as BK virus (BKV), infects up to 90% of the general
population. However, significant clinical manifestations are rare and limited to individuals …

[HTML][HTML] BK polyomavirus in solid organ transplantation

HH Hirsch, P Randhawa… - American journal of …, 2013 - Elsevier
The human BK polyomavirus (BKV) is the major cause of polyomavirus-associated
nephropathy (PyVAN) putting 1–15% of kidney transplant patients at risk of premature …

The second international consensus guidelines on the management of BK polyomavirus in kidney transplantation

CN Kotton, N Kamar, D Wojciechowski, M Eder… - …, 2024 - journals.lww.com
BK polyomavirus (BKPyV) remains a significant challenge after kidney transplantation.
International experts reviewed current evidence and updated recommendations according …

Incidence of BK with tacrolimus versus cyclosporine and impact of preemptive immunosuppression reduction

DC Brennan, I Agha, DL Bohl… - American Journal of …, 2005 - Wiley Online Library
Our purposes were to determine the incidence of BK viruria, viremia or nephropathy with
tacrolimus (FK506) versus cyclosporine (CyA) and whether intensive monitoring and …

[HTML][HTML] Polyomavirus BK replication in de novo kidney transplant patients receiving tacrolimus or cyclosporine: a prospective, randomized, multicenter study

HH Hirsch, F Vincenti, S Friman, M Tuncer… - American journal of …, 2013 - Elsevier
Polyomavirus BK (BKV)-associated nephropathy causes premature kidney transplant (KT)
failure. BKV viruria and viremia are biomarkers of disease progression, but associated risk …

[HTML][HTML] Histological patterns of polyomavirus nephropathy: correlation with graft outcome and viral load

CB Drachenberg, JC Papadimitriou, HH Hirsch… - American Journal of …, 2004 - Elsevier
Polyomavirus-associated nephropathy (PVAN) is a significant cause of allograft loss. The
diagnosis requires allograft biopsy, but the impact of the histological features on diagnosis …

[HTML][HTML] The role of polyomaviruses in human disease

M Jiang, JR Abend, SF Johnson, MJ Imperiale - Virology, 2009 - Elsevier
The human polyomaviruses, BK virus and JC virus, have long been associated with serious
diseases including polyomavirus nephropathy and progressive multifocal …

BK virus: opportunity makes a pathogen

HH Hirsch, DR Snydman - Clinical Infectious Diseases, 2005 - academic.oup.com
More than 70% of the general population worldwide has serological evidence of exposure to
Polyomavirus hominis type 1, better known as BK virus (BKV). BKV infection typically occurs …

Treatment of polyomavirus infection in kidney transplant recipients: a systematic review

O Johnston, D Jaswal, JS Gill, S Doucette… - …, 2010 - journals.lww.com
Background. Polyomavirus-associated nephropathy (PVAN) is an important cause of kidney
graft loss but there is no consensus on its management. This study aimed to systematically …