Long-term consequences of traumatic brain injury: current status of potential mechanisms of injury and neurological outcomes
HM Bramlett, WD Dietrich - Journal of neurotrauma, 2015 - liebertpub.com
Traumatic brain injury (TBI) is a significant clinical problem with few therapeutic interventions
successfully translated to the clinic. Increased importance on the progressive, long-term …
successfully translated to the clinic. Increased importance on the progressive, long-term …
Blood− brain barrier breakdown and neovascularization processes after stroke and traumatic brain injury
R Prakash, ST Carmichael - Current opinion in neurology, 2015 - journals.lww.com
Our understanding of BBB breakdown acutely after the cerebrovascular injury has come a
long way; however, we lack a clear understanding of the course of BBB disruption and BBB …
long way; however, we lack a clear understanding of the course of BBB disruption and BBB …
[HTML][HTML] Brain–immune interactions and neuroinflammation after traumatic brain injury
Traumatic brain injury (TBI) is the principal cause of death and disability in children and
young adults. Clinical and preclinical research efforts have been carried out to understand …
young adults. Clinical and preclinical research efforts have been carried out to understand …
Delayed increases in microvascular pathology after experimental traumatic brain injury are associated with prolonged inflammation, blood–brain barrier disruption …
OY Glushakova, D Johnson, RL Hayes - Journal of neurotrauma, 2014 - liebertpub.com
Traumatic brain injury (TBI) is a significant risk factor for chronic traumatic encephalopathy
(CTE), Alzheimer's disease (AD), and Parkinson's disease (PD). Cerebral microbleeds, focal …
(CTE), Alzheimer's disease (AD), and Parkinson's disease (PD). Cerebral microbleeds, focal …
Chronic cerebrovascular dysfunction after traumatic brain injury
A Jullienne, A Obenaus, A Ichkova… - Journal of …, 2016 - Wiley Online Library
Traumatic brain injuries (TBI) often involve vascular dysfunction that leads to long‐term
alterations in physiological and cognitive functions of the brain. Indeed, all the cells that form …
alterations in physiological and cognitive functions of the brain. Indeed, all the cells that form …
[HTML][HTML] Epilepsy related to traumatic brain injury
A Pitkänen, R Immonen - Neurotherapeutics, 2014 - Elsevier
Post-traumatic epilepsy accounts for 10–20% of symptomatic epilepsy in the general
population and 5% of all epilepsy. During the last decade, an increasing number of …
population and 5% of all epilepsy. During the last decade, an increasing number of …
[HTML][HTML] Disruptions in resting state functional connectivity and cerebral blood flow in mild traumatic brain injury patients
C Sours, J Zhuo, S Roys, K Shanmuganathan… - PLoS …, 2015 - journals.plos.org
Mild traumatic brain injury (mTBI) is often occult to conventional imaging techniques.
However, there is growing evidence that mTBI patients who lack evidence of structural …
However, there is growing evidence that mTBI patients who lack evidence of structural …
[HTML][HTML] Etiology matters–genomic DNA methylation patterns in three rat models of acquired epilepsy
This study tested the hypothesis that acquired epileptogenesis is accompanied by DNA
methylation changes independent of etiology. We investigated DNA methylation and gene …
methylation changes independent of etiology. We investigated DNA methylation and gene …
Chronic histopathological and behavioral outcomes of experimental traumatic brain injury in adult male animals
The purpose of this review is to survey the use of experimental animal models for studying
the chronic histopathological and behavioral consequences of traumatic brain injury (TBI) …
the chronic histopathological and behavioral consequences of traumatic brain injury (TBI) …
Modelling traumatic brain injury and posttraumatic epilepsy in rodents
RD Brady, PM Casillas-Espinosa, DV Agoston… - Neurobiology of …, 2019 - Elsevier
Posttraumatic epilepsy (PTE) is one of the most debilitating and understudied consequences
of traumatic brain injury (TBI). It is challenging to study the effects, underlying …
of traumatic brain injury (TBI). It is challenging to study the effects, underlying …