The genus Enterovirus (EV) of the family Picornaviridae includes poliovirus,
coxsackieviruses, echoviruses, numbered enteroviruses and rhinoviruses. These diverse …

New generation sequencing is greatly expanding the capacity to examine the composition of
mutant spectra of viral quasispecies in infected cells and host organisms. Here we review …

As a result of the redundancy of the genetic code, adjacent pairs of amino acids can be
encoded by as many as 36 different pairs of synonymous codons. A species-specific “codon …

The Picornaviridae represent a large family of small plus-strand RNA viruses that cause a
bewildering array of important human and animal diseases. Morphogenesis is the least …

Half a century ago scientists attempted the detection of poliovirus in water. Since then other
enteric viruses responsible for gastroenteritis and hepatitis have replaced enteroviruses as …

RNA recombination is a major driving force in the evolution and genetic architecture shaping
of enteroviruses. In particular, intertypic recombination is implicated in the emergence of …

Successful control measures have interrupted the local transmission of human infectious
diseases such as measles, malaria and polio, and saved and improved billions of lives …

In spite of decades-long studies, the mechanism of morphogenesis of plus-stranded RNA
viruses belonging to the genus Enterovirus of Picornaviridae, including poliovirus (PV), is …

Rapid progress in DNA synthesis and sequencing is spearheading the deliberate, large-
scale genetic alteration of organisms. These new advances in DNA manipulation have been …

Rhinoviruses and enteroviruses are leading causes of respiratory infections. To evaluate
genotypic diversity and identify forces shaping picornavirus evolution, we screened persons …