Stimuli-responsive ferroptosis for cancer therapy

N Kang, S Son, S Min, H Hong, C Kim, J An… - Chemical Society …, 2023 - pubs.rsc.org
Ferroptosis, an iron-dependent programmed cell death mechanism, is regulated by distinct
molecular pathways of lipid peroxidation caused by intracellular iron supplementation and …

Bioactive inorganic nanomaterials for cancer theranostics

Z Pei, H Lei, L Cheng - Chemical Society Reviews, 2023 - pubs.rsc.org
Bioactive materials are a special class of biomaterials that can react in vivo to induce a
biological response or regulate biological functions, thus achieving a better curative effect …

Ternary alloy PtWMn as a Mn nanoreservoir for high‐field MRI monitoring and highly selective ferroptosis therapy

G Guan, C Zhang, H Liu, Y Wang, Z Dong… - Angewandte …, 2022 - Wiley Online Library
Ferroptosis exhibits potential to damage drug‐resistant cancer cells. However, it is still
restricted with the “off‐target” toxicity from the undesirable leakage of metal ions from …

Steric effects in the deposition mode and drug-delivering efficiency of nanocapsule-based multilayer films

L Xu, Z Chu, J Zhang, T Cai, X Zhang, Y Li, H Wang… - ACS …, 2022 - ACS Publications
Using surface-initiated atom transfer radical polymerization (ATRP), block polymers with a
series of quaternization degrees were coated on the surface of silica nanocapsules (SNCs) …

New anti-cancer explorations based on metal ions

H Hu, Q Xu, Z Mo, X Hu, Q He, Z Zhang… - Journal of …, 2022 - Springer
Due to the urgent demand for more anti-cancer methods, the new applications of metal ions
in cancer have attracted increasing attention. Especially the three kinds of the new mode of …

Hybrid biomimetic membrane coated particles-mediated bacterial ferroptosis for acute MRSA pneumonia

H Hu, SY Hua, X Lin, F Lu, W Zhang, L Zhou, J Cui… - ACS …, 2023 - ACS Publications
Acute methicillin resistant Staphylococcus aureus (MRSA) pneumonia is one of the most
frequently seen lung infection diseases with high morbidity and mortality. It is urgent to …

[HTML][HTML] Magnetic nanoparticles for ferroptosis cancer therapy with diagnostic imaging

MJ Ko, S Min, H Hong, W Yoo, J Joo, YS Zhang… - Bioactive Materials, 2024 - Elsevier
Ferroptosis offers a novel method for overcoming therapeutic resistance of cancers to
conventional cancer treatment regimens. Its effective use as a cancer therapy requires a …

Ferroptosis: challenges and opportunities for nanomaterials in cancer therapy

Q Liu, Y Zhao, H Zhou, C Chen - Regenerative Biomaterials, 2023 - academic.oup.com
Ferroptosis, a completely new form of regulated cell death, is mainly caused by an
imbalance between oxidative damage and reductive protection and has shown great anti …

Activatable semiconducting polymer nanoinducers amplify oxidative damage via sono-ferroptosis for synergistic therapy of bone metastasis

Y Zhang, Q Zhang, F Wang, M Li, X Shi, J Li - Nano Letters, 2023 - ACS Publications
Bone metastases are secondary malignant tumors that commonly occur after the spread of
advanced cancer cells. We herein report the activatable semiconducting polymer …

Synergistic functional nanomedicine enhances ferroptosis therapy for breast tumors by a blocking defensive redox system

S Chen, J Yang, Z Liang, Z Li, W Xiong… - … Applied Materials & …, 2023 - ACS Publications
The upregulation of dihydroorotate dehydrogenase (DHODH) redox systems inside tumor
cells provides a powerful shelter against lipid peroxidation (LPO), impeding ferroptosis …