Oral squamous cell carcinoma (OSCC) represents 95% of all forms of head and neck
cancers. The five-year survival rate of OSCC patients has been reported approximately 50 …

Background There is a great interest in developing biomarkers to enhance early detection
and clinical management of tongue squamous cell carcinoma (TSCC). However, the …

Checkpoint inhibitors (CPIs) augment adaptive immunity. Systematic pan-tumor analyses
may reveal the relative importance of tumor-cell-intrinsic and microenvironmental features …

Cyclin D1 promotes cell cycle progression during G1 phase, a key event in G1‐S transition.
The protein is encoded by gene CCND 1, located in chromosomal band 11q13. Cyclin D1 …

Objectives We aimed to investigate genetic alterations in oral tongue squamous cell
carcinoma (OTSCC) based on age and the clinical significance of these alterations in young …

We investigated the relationship of different primary subsites together with their pathological
features on the survival of oral cavity squamous cell carcinoma (OCSCC) patients. We …

Background Metformin, which is widely used as an antidiabetic agent, has recently been
reported to reduce cancer risk and improve prognosis in certain malignancies. However, the …

Squamous cell carcinoma (SCC) is the most common epithelial malignancy in the oral
cavity. SCCs and their variants constitute over 90% of oral malignancies, and the disease is …

Deregulated cell cycle can contribute to the unscheduled proliferation in cancer cells.
Overexpression of cell cycle regulators CDK4 and Cyclin D1 has been reported in many …

Cutaneous squamous cell carcinoma (cSCC) is the second most common cancer and a
leading cause of cancer mortality among solid organ transplant recipients. MicroRNAs (miR) …