Ca2+ dynamics in interstitial cells: foundational mechanisms for the motor patterns in the gastrointestinal tract

KM Sanders, BT Drumm, CA Cobine… - Physiological …, 2024 - journals.physiology.org
The gastrointestinal (GI) tract displays multiple motor patterns that move nutrients and
wastes through the body. Smooth muscle cells (SMCs) provide the forces necessary for GI …

Structure and organization of interstitial cells of Cajal in the gastrointestinal tract

T Komuro - The Journal of physiology, 2006 - Wiley Online Library
The morphological features of interstitial cells of Cajal (ICC) in the gastrointestinal (GI) tract
are described based on observations of laboratory animals including mice, rats and guinea …

Vagal afferent innervation of the rat fundic stomach: morphological characterization of the gastric tension receptor

HR Berthoud, TL Powley - Journal of Comparative Neurology, 1992 - Wiley Online Library
Although the gastric tension receptor has been characterized behaviorally and
electrophysiologically quite well, its location and structure remains elusive. Therefore, the …

Functional gap junctions in the Schwann cell myelin sheath

RJ Balice-Gordon, LJ Bone, SS Scherer - The Journal of cell biology, 1998 - rupress.org
The Schwann cell myelin sheath is a multilamellar structure with distinct structural domains
in which different proteins are localized. Intracellular dye injection and video microscopy …

Gut macrophages: key players in intestinal immunity and tissue physiology

PA Muller, F Matheis, D Mucida - Current opinion in immunology, 2020 - Elsevier
Highlights•Distinct populations of intestinal macrophages segregated both transcriptionally
and anatomically, exist in the mouse and human.•The intestine hosts long-lived macrophage …

Ultrastructural characterization of the interstitial cells of Cajal

T Komuro, K Seki, K Horiguchi - Archives of histology and cytology, 1999 - jstage.jst.go.jp
抄録 Recent studies on the interstitial cells of Cajal (ICC) have determined ultrastructural
criteria for the identification of these previously enigmatic cells. This review deals with the …

Two independent networks of interstitial cells of Cajal work cooperatively with the enteric nervous system to create colonic motor patterns

JD Huizinga, S Martz, V Gil, XY Wang… - Frontiers in …, 2011 - frontiersin.org
Normal motility of the colon is critical for quality of life and efforts to normalize abnormal
colon function have had limited success. A better understanding of control systems of …

Comparative morphology of interstitial cells of Cajal: ultrastructural characterization

T Komuro - Microscopy research and technique, 1999 - Wiley Online Library
The shape, distribution, and ultrastructural features of interstitial cells of Cajal (ICC) of
different tissue layers and organs of the rat and guinea‐pig digestive tract were described …

Interstitial cells of Cajal (ICC) and gastrointestinal stromal tumor (GIST): facts, speculations, and myths

KW Min, M Leabu - Journal of cellular and molecular medicine, 2006 - Wiley Online Library
Interstitial cells of Cajal (ICC) is a peculiar cell network composed of cells having processes
described by the eminent Spanish neuroanatomist of the 19th century, S. Ramon y Cajal …

One hundred years of interstitial cells of Cajal

L Thuneberg - Microscopy research and technique, 1999 - Wiley Online Library
This review is a portrayal of the evolution of ideas involving the interstitial cells of Cajal in
changing disguises as dull fibroblasts, not very exciting Schwann cells, or perhaps quite …