Cell-type diversity in the bed nucleus of the stria terminalis to regulate motivated behaviors

MM Ortiz-Juza, RA Alghorazi… - Behavioural brain …, 2021 - Elsevier
Over the past few decades, the bed nucleus of the stria terminalis (BNST) gained popularity
as a unique brain region involved in regulating motivated behaviors related to …

Targeting vesicular glutamate transporter machinery: implications on metabotropic glutamate receptor 5 signaling and behavior

KS Ibrahim, KS Abd-Elrahman, S El Mestikawy… - Molecular …, 2020 - ASPET
Cross talk between both pre-and postsynaptic components of glutamatergic
neurotransmission plays a crucial role in orchestrating a multitude of brain functions …

[HTML][HTML] Predicting the distribution of serotonergic axons: a supercomputing simulation of reflected fractional Brownian motion in a 3D-mouse brain model

S Janušonis, JH Haiman, R Metzler… - Frontiers in Computational …, 2023 - frontiersin.org
The self-organization of the brain matrix of serotonergic axons (fibers) remains an unsolved
problem in neuroscience. The regional densities of this matrix have major implications for …

[HTML][HTML] Neural serotonergic circuits for controlling long-term voluntary alcohol consumption in mice

A Belmer, R Depoortere, K Beecher… - Molecular …, 2022 - nature.com
Alcohol-use-disorders are chronic relapsing illnesses, often co-morbid with anxiety. We
have previously shown using the “drinking-in-the-dark” model in mice that the stimulation of …

[HTML][HTML] Sucrose consumption alters serotonin/glutamate co-localisation within the prefrontal cortex and hippocampus of mice

K Beecher, J Wang, A Jacques, N Chaaya… - Frontiers in Molecular …, 2021 - frontiersin.org
The overconsumption of sugar-sweetened food and beverages underpins the current rise in
obesity rates. Sugar overconsumption induces maladaptive neuroplasticity to decrease …

Optogenetic stimulation of midbrain dopamine neurons produces striatal serotonin release

M Dagher, KA Perrotta, SA Erwin… - ACS chemical …, 2022 - ACS Publications
Targeting neurons with light-driven opsins is widely used to investigate cell-specific
responses. We transfected midbrain dopamine neurons with the excitatory opsin Chrimson …

Chemogenetic activation of VGLUT3-expressing neurons decreases movement

O Kljakic, AE Hogan-Cann, H Yang, B Dover… - European Journal of …, 2022 - Elsevier
Vesicular glutamate transporters (VGLUTs) are responsible for the storage of glutamate into
secretory vesicles. The VGLUT3 isoform is mainly expressed in neurons that secrete other …

[HTML][HTML] A role for serotonin in modulating opposing drive and brake circuits of impulsivity

SS Desrochers, MG Spring… - Frontiers in behavioral …, 2022 - frontiersin.org
Impulsivity generally refers to a deficit in inhibition, with a focus on understanding the neural
circuits which constitute the “brake” on actions and gratification. It is likely that increased …

A retinal circuit for the suppressed-by-contrast receptive field of a polyaxonal amacrine cell

Y Jia, S Lee, Y Zhuo, ZJ Zhou - Proceedings of the National …, 2020 - National Acad Sciences
Amacrine cells are a diverse population of interneurons in the retina that play a critical role
in extracting complex features of the visual world and shaping the receptive fields of retinal …

[HTML][HTML] Structural connectivity and subcellular changes after antidepressant doses of ketamine and Ro 25-6981 in the rat: an MRI and immuno-labeling study

R Pascual-Antón, A Blasco-Serra… - Brain Structure and …, 2021 - Springer
Ketamine has rapid and robust antidepressant effects. However, unwanted psychotomimetic
effects limit its widespread use. Hence, several studies examined whether GluN2B-subunit …