Despite decades of bile acid research, diverse biological roles for bile acids have been
discovered recently due to developments in understanding the human microbiota. As …

Antibiotics played an important role in controlling the development of enteric infection.
However, the emergence of antibiotic resistance and gut dysbiosis led to a growing interest …

Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a natural
product class that has undergone significant expansion due to the rapid growth in genome …

The microbiomes on human body surfaces affect health in multiple ways. They include not
only commensal or mutualistic bacteria but also potentially pathogenic bacteria, which can …

In recent decades, bacteriocins have received substantial attention as antimicrobial
compounds. Although bacteriocins have been predominantly exploited as food …

Currently, the emergence and ongoing dissemination of antimicrobial resistance among
bacteria are critical health and economic issue, leading to increased rates of morbidity and …

Many intestinal pathogens, including Clostridioides difficile, use mucus-derived sugars as
crucial nutrients in the gut. Commensals that compete with pathogens for such nutrients are …

The gastrointestinal (GI) tract represents a unique challenge to the mammalian immune
system. It must tolerate the presence of the luminal microbiota and thus not respond to their …

The gut microbiome is critical in providing resistance against colonization by exogenous
microorganisms. The mechanisms via which the gut microbiota provide colonization …

The human gastrointestinal tract hosts a diverse network of microorganisms, collectively
known as the microbiota that plays an important role in health and disease. For instance, the …